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Table 1 The rate of cytokine secretion +/- standard error over 9 days by microglia infected with HIV and / or treated with 20 nM RAL (pg × mL -1× day -1 )

From: Cytokine secretion from brain macrophages infected with human immunodeficiency virus in vitro and treated with raltegravir

Condition TNF-α IL-10 IL-8
Control 3.09 ± 1.8 1.2 ± 0.16 245 ± 6.2
HIV 5.54 ± 1.8 1.07 ± 0.12 232 ± 8.1
RAL 10.9 ± 3.8 1.25 ± 0.15 268 ± 9.9
HIV + RAL 2.2 ± 1.0 0.33 ± 0.14 132 ± 5.0
a P-value 0.04 < 0.001 < 0.0001
  1. aFor a significant effect of treatment Condition on the rate of cytokine secretion against the null hypothesis that all treatments were the same.