Skip to main content

Table 3 Diagnosis accuracy of the Candida Score regarding the risk of proven and/or probable IC, as compared with our local guidelines

From: Empirical antifungal therapy with an echinocandin in critically-ill patients: prospective evaluation of a pragmatic Candida score-based strategy in one medical ICU

  Sensitivity (95% CI) Specificity (95% CI) Positive predictive value (95% CI) Negative predictive value (95% CI) Positive likelihood ratio Area under the ROC curve (95% CI)
Candida score & Proven IC 81.0% (58.1–94.5) 47.1% (36.1–58.2) 27.4% (16.8–40.2) 90.9% (78.3–97.5) 1.53 0.64 (0.51–0.76)
Candida score & Proven + probable IC 89.7% (75.8–97.1) 59.7% (47.0–71.5) 56.4% (43.3–69.0) 90.9% (78.3–97.5) 2.23 0.75 (0.65–0.84)
Local guidelines & Proven IC 42.9% (21.8–66.0) 64.7% (53.6–74.8) 23.1% (11.1–39.3) 82.1% (70.8–90.4) 1.21 0.54 (0.40–0.68)
Local guidelines & Proven + probable IC 69.2% (52.4–83.0) 82.1% (70.8–90.4) 69.2% (52.4–83.0) 82.1% (70.8–90.4) 3.86 0.76 (0.66–0.86)
  1. IC: invasive candidiasis; CI: confidence interval; ROC : receiver operating characteristics.