Empirical therapy (n = 39) | Definite therapy (n = 12) | p | |
---|---|---|---|
Time elapsed between ICU admission and AFT (days) | 8.8 (9.9) | 9.0 (6.8) | 0.96 |
Time between BC and AFT (days)* | 0.4 (0.5) | 2.8 (0.8) | <0.01 |
AFT duration (days) | 9.2 (6.0) | 9.1 (6.4) | 0.95 |
Echinocandin therapy duration (days) | 6.7 (4.7) | 5.7 (4.2) | 0.54 |
Fluconazole therapy duration (days) | 2.6 (5.1) | 3.4 (5.2) | 0.62 |
Septic shock (N. [%]) | 31 (79.5) | 6 (50.0) | 0.04 |
RRT (N. [%]) | 22 (56.4) | 4 (33.3) | 0.16 |
SOFA D1 | 8.8 (3.0) | 8.4 (3.0) | 0.14 |
PCT D1 (pg/L) | 3.6 (6.6) | 4.2 (10.6) | 0.56 |
Proven bacterial infection prior to AFT (N. [%]) | 14 (46.7) | 9 (42.8) | 0.79 |
Outcomes Length of ICU stay (days) | 21.4 (15.7) | 25.6 (22.4) | 0.47 |
MV duration (days) | 15.7 (13.3) | 22.4 (24.7) | 0.22 |
Vasoactive support duration while receiving AFT (days) | 3.8 (2.9) | 2.3 (2.6) | 0.11 |
ICU mortality (N. [%]) | 20 (51.2) | 6 (50.0) | 0.93 |
In-hospital mortality (N. [%]) | 25 (64.1) | 9 (75.0) | 0.14 |