From: Common subclinical hypothyroidism during Whipple’s disease
HLA type | Number of individuals | Cohort vs. control | |||||
---|---|---|---|---|---|---|---|
Locus | Allele | Hypothyroidism | Control | Odds Ratio | P 1 | ||
HLA-A | 01 | 0 | 0% | 36 | 28% | N.A | 0.19 |
02 | 5 | 71% | 55 | 42% | 3.41 | > 0.2 | |
03 | 2 | 29% | 32 | 25% | 1.23 | ||
24 | 2 | 29% | 26 | 20% | 1.60 | ||
26 | 1 | 14% | 11 | 8% | 1.80 | ||
29 | 1 | 14% | 14 | 11% | 1.38 | ||
32 | 1 | 14% | 18 | 14% | 1.04 | ||
68 | 2 | 29% | 14 | 11% | 3.31 | 0.19 | |
Total | 7 | 130 | |||||
HLA-B | 07 | 1 | 14% | 19 | 15% | 0.97 | |
14 | 2 | 29% | 12 | 9% | 3.93 | 0.15 | |
15 | 2 | 29% | 20 | 15% | 2.20 | ||
27 | 1 | 14% | 8 | 6% | 2.54 | ||
35 | 1 | 14% | 20 | 15% | 0.92 | ||
38 | 1 | 14% | 5 | 4% | 4.17 | > 0.2 | |
39 | 1 | 14% | 6 | 5% | 3.44 | > 0.3 | |
41 | 1 | 14% | 4 | 3% | 5.25 | > 0.2 | |
44 | 2 | 29% | 34 | 26% | 1.13 | ||
51 | 1 | 14% | 15 | 12% | 1.28 | ||
55 | 1 | 14% | 8 | 6% | 2.54 | ||
Total | 7 | 130 | |||||
HLA-C | 03 | 3 | 43% | 26 | 20% | 3.00 | 0.16 |
04 | 1 | 14% | 22 | 17% | 0.82 | ||
05 | 2 | 29% | 21 | 16% | 2.08 | ||
06 | 1 | 14% | 26 | 20% | 0.67 | ||
07 | 3 | 43% | 66 | 51% | 0.73 | ||
08 | 2 | 29% | 13 | 10% | 3,60 | 0,17 | |
12 | 1 | 14% | 18 | 14% | 1,04 | ||
15 | 1 | 14% | 7 | 5% | 2,93 | ||
Total | 7 | 130 | |||||
HLA-DRB1 | 01 | 2 | 25% | 27 | 21% | 2,29 | |
03 | 1 | 13% | 24 | 19% | 0,63 | ||
04 | 2 | 25% | 36 | 28% | 0,87 | ||
07 | 1 | 13% | 19 | 15% | 0,83 | ||
08 | 1 | 13% | 9 | 7% | 1,92 | ||
11 | 3 | 38% | 36 | 28% | 1,57 | ||
13 | 3 | 38% | 38 | 29% | 1,45 | ||
14 | 1 | 13% | 13 | 10% | 1,29 | ||
15 | 1 | 13% | 24 | 19% | 0,63 | ||
Total | 8 | 130 | |||||
HLA-DQB1 | 02 | 2 | 25% | 37 | 29% | 0,84 | |
03 | 4 | 50% | 93 | 72% | 0,40 | > 0.2 | |
04 | 1 | 13% | 5 | 4% | 3,57 | > 0.3 | |
05 | 4 | 50% | 48 | 37% | 1,71 | ||
06 | 3 | 38% | 56 | 43% | 0,79 | ||
Total | 8 | 130 |