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Table 5 Proportions of infection or clinical morbidity among household contacts of children and adults among three TIV vaccination status groups during the three consecutive influenza seasons

From: Geographical heterogeneity and influenza infection within households

 

1st Year

 

2nd Year

 

3rd Year

 

Children, Number (proportion)

TIV(-)

TIV(+)

P

TIV(-)

Partial TIV

TIV(+)

P

TIV(-)

Partial TIV

TIV(+)

P

 

N = 37

N = 43

 

N = 72

N = 38

N = 14

 

N = 31

N = 32

N = 74

 

4-fold increase

           

  H1N1

6(0.16)

6(0.14)

 

29(0.40)

10(0.26)

3(0.21)

 

13(0.42)

12(0.38)

31(0.42)

 

  H3N2

4(0.11)

14(0.33)

 

30(0.42)

17(0.45)

4(0.29)

 

11(0.35)

6(0.19)

26(0.35)

 

  B

4(0.11)

3(0.07)

 

35(0.49)

17(0.45)

7(0.50)

 

6(0.19)

14(0.44)

18(0.24)

 

  pH1N1

-

-

 

55(0.76)

27(0.71)

13(0.93)

 

-

-

-

 

Any 4-fold increase

14(0.38)

20(0.47)

 

44(0.61)

23(0.61)

7(0.50)

 

22(0.71)

21(0.66)

52(0.70)

 

Symptoms

           

  Any

17(0.46)

29(0.67)

 

36(0.50)

22(0.58)

9(0.64)

 

19(0.61)

13(0.41)

37(0.50)

 

  Fever

5(0.14)

14(0.33)

 

7(0.10)

1(0.03)

1(0.07)

 

3(0.10)

6(0.19)

9(0.12)

 

  Fever plus any two symptoms

3(0.08)

10(0.23)

 

4(0.06)

0(0.00)

0(0.00)

 

1(0.03)

4(0.13)

7(0.09)

 

Any 4-fold increase plus any symptoms

5(0.14)

15(0.35)

*

24(0.33)

13(0.34)

5(0.36)

 

27(0.87)

24(0.75)

62(0.84)

 

Adults, Number (proportion)

TIV(-)

TIV(+)

P

TIV(-)

Partial TIV

TIV(+)

P

TIV(-)

Partial TIV

TIV(+)

P

 

N = 98

N = 116

 

N = 222

N = 111

N = 109

 

N = 77

N = 74

N = 249

 

Any 4-fold increase

           

  H1N1

0(0.00)

2(0.02)

 

70(0.32)

46(0.41)

41(0.38)

 

10(0.13)

19(0.26)

60(0.24)

 

  H3N2

9(0.09)

17(0.15)

 

57(0.26)

38(0.34)

41(0.38)

*

3(0.04)

0(0.00)

6(0.02)

 

  B

5(0.05)

3(0.03)

 

70(0.32)

45(0.41)

38(0.35)

 

4(0.05)

6(0.08)

18(0.07)

 

  pH1N1

-

-

 

109(0.49)

57(0.51)

55(0.50)

 

-

-

-

 

Any 4-fold increase

14(0.14)

20(0.17)

 

135(0.61)

74(0.67)

75(0.69)

 

11(0.14)

20(0.27)

64(0.26)

 

Symptoms

           

  Any

43(0.44)

52(0.45)

 

55(0.25)

34(0.31)

39(0.36)

*

30(0.39)

31(0.42)

105(0.42)

 

  Fever

9(0.09)

5(0.04)

 

1(0.00)

4(0.04)

2(0.02)

 

2(0.03)

1(0.01)

7(0.03)

 

  Fever plus any two symptoms

0(0.00)

1(0.01)

 

0(0.00)

0(0.00)

0(0.00)

 

1(0.01)

0(0.00)

5(0.02)

 

Any 4-fold increase plus any symptoms

7(0.07)

7(0.06)

 

39(0.18)

24(0.22)

24(0.22)

 

38(0.49)

42(0.57)

131(0.53)

 
  1. *P < 0.05.