Skip to main content

Table 3 Biochemical data in pregnant and non-pregnant AHB patients at admission, discharge and final follow-up

From: Clinical features and outcome of acute hepatitis B in pregnancy

Variables Non-pregnant AHB patients N = 87 Pregnant AHB patients N = 22 P
At admission    
Days from disease onset to examination 11.8 ± 7.3 11.3 ± 4.1 0.70
ALT(IU/L) 1237 (274–3615) 1025 (285–1797) 0.039
ALT > 1600 IU/L 27 (31.0%) 1 (4.5%) 0.01
Bilirubin(μmol/L) 66.4 (8.2-549.7) 140 (29.6-289.1) 0.005
Bilirubin > 25 μmol/L 69 (79.3%) 22 (100%) 0.02
Albumin(g/L) 39.0 (28–66) 33.0 (23.0-42.3) < 0.001
Albumin < 35 g/L 12 (13.8%) 14 (63.6%) < 0.001
GGT(IU/L) 95 (22–425) 32.5 (21–159) < 0.001
GGT > 64 IU/L 68 (78.1%) 4 (18.2%) < 0.001
At discharge    
Days from disease onset to examination 38.6 ± 11.9 34.2 ± 7.1 0.11
ALT(IU/L) 28 (7–712) 17 (9–128) 0.004
ALT normalization 56 (64.4%) 20 (90.9%) 0.02
Bilirubin(μmol/L) 15.2 (4.2-212.5) 19.7 (8–61.4) 0.27
Bilirubin normalization 65 (74.7%) 17 (77.3%) 0.80
Albumin(g/L) 40.4 (32–48.4) 35 (30–38.8) < 0.001
Albumin normalization 85 (97.7%) 12 (54.5%) < 0.001
GGT(IU/L) 48.0 (10–227) 28.5 (12–93) < 0.001
GGT normalization 60 (69.0%) 20 (90.9%) 0.04
Final follow-up    
Months from disease onset to examination 7.0 ± 0.8 6.9 ± 0.7 0.54
ALT(IU/L) 20 (5–68) 12 (6–37) 0.015
ALT normalization 83 (95.4%) 22 (100%) 0.31
Bilirubin(μmol/L) 12.1 (4.2-56) 13 (5–22) 0.47
Bilirubin normalization 83 (94.4%) 22 (100%) 0.31
Albumin(g/L) 43 (36–48.5) 39.5 (34–43.0) < 0.001
Albumin < 35 g/L 0 (0%) 3 (13.6%) < 0.001
GGT(IU/L) 37 (10–87) 20 (12–30) < 0.001
GGT normalization 80 (91.9%) 22 (100%) 0.17
  1. NOTE. Data are expressed as mean ± SD, median(min-max), or n (%) of patients. AHB, acute hepatitis B; ALT, alanine aminotransferase; GGT, gamma-glutmyltransferase.