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Table 3 Biochemical data in pregnant and non-pregnant AHB patients at admission, discharge and final follow-up

From: Clinical features and outcome of acute hepatitis B in pregnancy

Variables

Non-pregnant AHB patients N = 87

Pregnant AHB patients N = 22

P

At admission

   

Days from disease onset to examination

11.8 ± 7.3

11.3 ± 4.1

0.70

ALT(IU/L)

1237 (274–3615)

1025 (285–1797)

0.039

ALT > 1600 IU/L

27 (31.0%)

1 (4.5%)

0.01

Bilirubin(μmol/L)

66.4 (8.2-549.7)

140 (29.6-289.1)

0.005

Bilirubin > 25 μmol/L

69 (79.3%)

22 (100%)

0.02

Albumin(g/L)

39.0 (28–66)

33.0 (23.0-42.3)

< 0.001

Albumin < 35 g/L

12 (13.8%)

14 (63.6%)

< 0.001

GGT(IU/L)

95 (22–425)

32.5 (21–159)

< 0.001

GGT > 64 IU/L

68 (78.1%)

4 (18.2%)

< 0.001

At discharge

   

Days from disease onset to examination

38.6 ± 11.9

34.2 ± 7.1

0.11

ALT(IU/L)

28 (7–712)

17 (9–128)

0.004

ALT normalization

56 (64.4%)

20 (90.9%)

0.02

Bilirubin(μmol/L)

15.2 (4.2-212.5)

19.7 (8–61.4)

0.27

Bilirubin normalization

65 (74.7%)

17 (77.3%)

0.80

Albumin(g/L)

40.4 (32–48.4)

35 (30–38.8)

< 0.001

Albumin normalization

85 (97.7%)

12 (54.5%)

< 0.001

GGT(IU/L)

48.0 (10–227)

28.5 (12–93)

< 0.001

GGT normalization

60 (69.0%)

20 (90.9%)

0.04

Final follow-up

   

Months from disease onset to examination

7.0 ± 0.8

6.9 ± 0.7

0.54

ALT(IU/L)

20 (5–68)

12 (6–37)

0.015

ALT normalization

83 (95.4%)

22 (100%)

0.31

Bilirubin(μmol/L)

12.1 (4.2-56)

13 (5–22)

0.47

Bilirubin normalization

83 (94.4%)

22 (100%)

0.31

Albumin(g/L)

43 (36–48.5)

39.5 (34–43.0)

< 0.001

Albumin < 35 g/L

0 (0%)

3 (13.6%)

< 0.001

GGT(IU/L)

37 (10–87)

20 (12–30)

< 0.001

GGT normalization

80 (91.9%)

22 (100%)

0.17

  1. NOTE. Data are expressed as mean ± SD, median(min-max), or n (%) of patients. AHB, acute hepatitis B; ALT, alanine aminotransferase; GGT, gamma-glutmyltransferase.