Table 1 Demographic and clinical characteristics of the children with SFTS in comparison with adult patients
From: Severe fever with thrombocytopenia syndrome in children: a case report
Characteristics | Pediatric patients | Adult patients (N = 180) | |||
|---|---|---|---|---|---|
Case1 | Case2 | Case3 | Case4 | ||
Demographic features | No. (%)/mean (SD) | ||||
Gender | Male | Female | Female | Male | 80 male (44.4) |
Age, y, | 6 | 7 | 4 | 15 | 57.5 (13.0) |
History of tick bite | Yes | No | No | Yes | 29 (16.1) |
Close contact with known SFTS patients | No | Yes | Yes | No | 12 (6.7) |
Mean (range) | |||||
Median days from syndromes to admission | 3 | 7 | 5 | 4 | 5 (1–38) |
Presenting with clinical manifestations on admission | No. (%) of patients | ||||
Fever | Yes | Yes | Yes | Yes | 177 (98.3) |
Malaise | Yes | Yes | Yes | Yes | 172 (95.6) |
Myalgias | No | No | No | No | 148 (82.2) |
Gastrointestinal syndromes | Yes | Yes | Yes | No | 116 (64.4) |
Cough | No | No | No | No | 63 (35.0) |
Sputum production | No | No | No | No | 46 (25.6) |
Dizziness | No | No | No | No | 42 (23.3) |
Headache | No | No | No | No | 35 (19.4) |
Dyspnea | No | No | No | No | 21 (11.7) |
Arthralgias | No | Yes | No | No | 13 (7.2) |
Lymphadenopathy | No | Yes | No | No | 78 (3.3) |
Hematuria | No | No | No | No | 33 (18.3) |
Petechia | No | No | Yes | No | 25 (13.9) |
Hematemesis | No | No | No | No | 13 (7.2) |
Gingival bleeding | No | No | No | No | 2 (1.1) |
Melena | No | No | No | No | 2 (1.1) |
Consciousness disorder | No | No | No | No | 36 (20.0) |
Laboratory measurements on admission | Mean ± SD | ||||
WBC (x109/L) | 2.3* | 1.83* | 2.9* | 3.3* | 3.0 ± 2.3 |
PLT (x109/L) | 118 | 87* | 107 | 148 | 71.3 ± 34.6 |
Neutrophils (%) | 52.9 | 41.7 | 37.3 | 72.5 | 62.0 ± 15.9 |
Lymphocyte (%) | 32.7 | 43.7 | 58.1 | 19.2 | 29.1 ± 13.0 |
With abnormal laboratory tests on admission | No. (%) of patients | ||||
AST >40 U/L | No (14) | Yes (521) | No (18) | No (39) | 148 (82.2) |
ALT >40 U/L | No (32) | Yes (178) | Yes (55) | No (19) | 115 (63.9) |
ALB <35 g/ | No (48.3) | No (42.5) | No (45.5) | No (44.4) | 78 (45.6) |
ALP >150 U/L | Yes (289) | Yes (239) | Yes (191) | No (132) | 14 (8.2) |
GGT >50 U/L | No (10) | Yes (52) | No (13) | No (15) | 49 (27.2) |
LDH >245 U/L | Yes (250) | Yes (545) | Yes (320) | No (236) | 136 (75.6) |
CK >232 U/L | No (89) | Yes (1167) | No (94) | Yes (1012) | 128 (71.1) |
BUN >7.8 mmol/L | No (5.68) | No (3.36) | No (4.59) | No (7.5) | 45 (25.0) |
CREA >97 mmol/L | No (30) | No (35) | No (35) | No (87) | 41 (22.8) |
Proteinuria | No | No | No | No | 55 (30.6) |
Outcome | |||||
Recovery | Yes | Yes | Yes | Yes | 144 (80.0) |
Adverse Outcome | No | No | No | No | 36 (20.0) |
Death | No | No | No | No | 25 (13.9) |