D
I
| Influenza A | Influenza B | Prevented |
---|
No vaccination | TIV or QIV | No vaccination | TIV | QIV | QIV-TIV | % |
---|
4 | 12644 | 6965 | 6743 | 4302 | 3785 | 517 | 4.6 |
(12548–12740) | (6896–7035) | (6681–6805) | (4256–4349) | (3741–3829) | (490–545) | (4.3-4.8) |
6
|
9820
|
5597
|
5229
|
3346
|
2951
|
395
|
4.3
|
(9750–9891)
|
(5550–5643)
|
(5183–5275)
|
(3313–3379)
|
(2920–2982)
|
(376–414)
|
(4.1-4.5)
|
8 | 8482 | 4944 | 4474 | 2924 | 2595 | 329 | 4.1 |
(8385–8579) | (4878–5010) | (4410–4539) | (2879–2970) | (2552–2638) | (305–354) | (3.8-4.4) |
10 | 7682 | 4524 | 4055 | 2631 | 2363 | 267 | 3.7 |
(7585–7780) | (4460–4589) | (3990–4119) | (2585–2676) | (2320–2406) | (243–291) | (3.3-4.0) |
12 | 7209 | 4259 | 3766 | 2476 | 2194 | 282 | 4.1 |
(7110–7307) | (4195–4323) | (3702–3831) | (2432–2520) | (2152–2236) | (257–306) | (3.7-4.5) |
- Average annual results (with 95% confidence intervals) obtained for the 20Â year evaluation period (calculated from 1,000 simulations for each combination of D
I
and vaccination strategy in a simulated population of about 80,000 individuals (2,000 simulations each for the baseline value of 6Â years; boldface line). The immunity loss rate (baseline value 1/(9.13Â years)) is varied to obtain the average duration of immunity given in the D
I
column; these values apply to A(H1N1) and to the B lineages. Due to the higher drift frequency, the resulting durations for A(H3N2) are lower: 3.2Â years, 4.5Â years, 5.5Â years, 6.4Â years and 7.1Â years, respectively. The last column shows what percentage of all influenza A and B infections which occur under TIV vaccination can additionally be prevented by QIV.