|
D
I
|
Influenza A
|
Influenza B
|
Prevented
|
|---|
|
No vaccination
|
TIV or QIV
|
No vaccination
|
TIV
|
QIV
|
QIV-TIV
|
%
|
|---|
|
4
|
12644
|
6965
|
6743
|
4302
|
3785
|
517
|
4.6
|
|
(12548–12740)
|
(6896–7035)
|
(6681–6805)
|
(4256–4349)
|
(3741–3829)
|
(490–545)
|
(4.3-4.8)
|
|
6
|
9820
|
5597
|
5229
|
3346
|
2951
|
395
|
4.3
|
|
(9750–9891)
|
(5550–5643)
|
(5183–5275)
|
(3313–3379)
|
(2920–2982)
|
(376–414)
|
(4.1-4.5)
|
|
8
|
8482
|
4944
|
4474
|
2924
|
2595
|
329
|
4.1
|
|
(8385–8579)
|
(4878–5010)
|
(4410–4539)
|
(2879–2970)
|
(2552–2638)
|
(305–354)
|
(3.8-4.4)
|
|
10
|
7682
|
4524
|
4055
|
2631
|
2363
|
267
|
3.7
|
|
(7585–7780)
|
(4460–4589)
|
(3990–4119)
|
(2585–2676)
|
(2320–2406)
|
(243–291)
|
(3.3-4.0)
|
|
12
|
7209
|
4259
|
3766
|
2476
|
2194
|
282
|
4.1
|
|
(7110–7307)
|
(4195–4323)
|
(3702–3831)
|
(2432–2520)
|
(2152–2236)
|
(257–306)
|
(3.7-4.5)
|
- Average annual results (with 95% confidence intervals) obtained for the 20 year evaluation period (calculated from 1,000 simulations for each combination of D
I
and vaccination strategy in a simulated population of about 80,000 individuals (2,000 simulations each for the baseline value of 6 years; boldface line). The immunity loss rate (baseline value 1/(9.13 years)) is varied to obtain the average duration of immunity given in the D
I
column; these values apply to A(H1N1) and to the B lineages. Due to the higher drift frequency, the resulting durations for A(H3N2) are lower: 3.2 years, 4.5 years, 5.5 years, 6.4 years and 7.1 years, respectively. The last column shows what percentage of all influenza A and B infections which occur under TIV vaccination can additionally be prevented by QIV.
