|
Gender
|
Female
|
1
| |
1
| |
| |
Male
|
1.29
|
0.70-2.35
|
1.14
|
0.59-2.20
|
|
Age
|
20-34
|
1
| |
1
| |
| |
35-49
|
1.96*
|
1.07-3.57
|
2.14*
|
1.11-4.14
|
| |
≥50
|
2.75**
|
1.50-5.05
|
2.97**
|
1.51-5.86
|
|
Body Mass Index
|
<18.5
|
1
| |
1
| |
| |
≥18.5
|
0.47**
|
0.31-0.73
|
0.33***
|
0.20-0.54
|
|
Diabetes
|
No
|
1
| |
1
| |
| |
Yes
|
2.47***
|
1.51-4.05
|
2.57**
|
1.46-4.52
|
|
Alcohol, within 6 months
|
Less than once a week
|
1
| |
-
| |
| |
Several times a week
|
0.52
|
0.26-1.05
| | |
| |
At least once a day
|
0.92
|
0.58-1.48
| | |
|
Smoking, within 6 months
|
Never smoked
|
1
| |
-
| |
| |
< 1 pack/day
|
1.71
|
0.99-2.97
| | |
| |
1 pack/day
|
1.14
|
0.66-1.97
| | |
| |
> 1 pack/day
|
1.03
|
0.57-1.89
| | |
|
Residence
|
Small city and town
|
1
| |
-
| |
| |
Large city
|
1.19
|
0.78-1.83
| | |
|
Education
|
High school, above
|
1
| |
-
| |
| |
Middle school, below or refusal
|
1.40
|
0.92-2.15
| | |
|
Occupation
|
Health care, professional and office work
|
1
| |
-
| |
| |
Service sector and laborer
|
1.35
|
0.66-2.76
| | |
| |
Unemployment and others
|
1.54
|
0.73-3.24
| | |
|
Chest X-ray
| | | | | |
|
Grade
|
Minimal or moderate
|
1
| |
-
| |
| |
Far advanced
|
2.09**
|
1.35-3.24
| | |
|
Cavity
|
No
|
1
| |
-
| |
| |
Yes or not clear
|
1.25
|
0.72-2.15
| | |
|
Nodular lesion
|
No
|
1
| |
-
| |
| |
Yes or not clear
|
1.44
|
0.60-3.48
| | |
|
Bilateral
|
Unilateral
|
1
| |
-
| |
| |
Bilateral
|
2.67**
|
1.38-5.18
| | |
|
Number of previous treatment episodes
|
0 (new case)
|
1
| |
-
| |
| |
1
|
1.7
|
0.90-3.22
| | |
| |
2
|
1.04
|
0.48-2.27
| | |
| |
≥3
|
4.66***
|
2.69-8.08
| | |
|
History of failure
|
No
|
1
| |
-
| |
| |
Yes
|
3.32***
|
2.11-5.22
| | |
|
History of TI
|
No
|
1
| |
-
| |
| |
Yes
|
2.26***
|
1.45-3.51
| | |
|
Number of significant regimen changes
|
0
|
1
| |
-
| |
| |
≥1
|
1.21
|
0.75-1.93
| | |
|
Drug Susceptibility pattern (n = 401)
|
DS
|
1
| |
1
| |
| |
Mono/poly-R
|
1.42
|
0.68-2.97
|
1.45
|
0.67-3.13
|
| |
Rif, mono-R
|
1.69
|
0.42-6.87
|
2.87
|
0.64-12.95
|
| |
MDR
|
3.39***
|
2.09-5.50
|
4.51***
|
2.64-7.68
|
