Independent influence of negative blood cultures and bloodstream infections on in-hospital mortality

BMC Infectious Diseases

Table 1 Description of study hospitalizations

	No blood culture (N=243 373, 81.9%)		1+ Blood culture, all negative (N=48 423, 16.3%)		1+ Blood culture, 1+ positive (N=5274, 1.8%)		All patients (N=297, 7%)
*Patient*
Mean age (SD)	53.2	20.2	62.3	18.8	63.4	17.9	54.8	20.2
Female	145 772	59.9	23 414	48.4	2403	45.6	171 589	57.8
Elixhauser score*: <0	11206	4.6	1719	3.6	212	4.0	13 137	4.4
0	140 027	57.5	12 461	25.7	1177	22.3	153 665	51.7
>0	91 140	37.9	34 243	70.7	3885	73.7	130 268	43.8
*Admission*
Emergent admission	135 962	55.9	43 914	90.7	4856	92.1	184 732	62.2
Admitted to surgical service	82 721	34.0	11 116	23.0	1012	19.2	94 849	31.9
Median death risk (IQR)**	0.4%	0.1-2.1	5.1%	1.2-15.6	8.0%	2.1-22.6	0.6%	0.17-4.0
LAP score****: 0	152 338	62.6	9742	20.1	804	15.2	162 884	54.8
>0	91 035	37.4	38 681	79.9	4470	84.8	134 186	45.2
*Hospitalization*
Intensive care unit***	4137	1.7	7845	16.2	1297	24.5	13 369	4.5
Surgical procedure***	66 928	27.5	8813	18.2	964	18.2	76 649	25.8
Neutrophils < 500 × 10⁹/L***	730	0.3	3147	6.5	609	11.5	4456	1.5
Immunosupressant***	6814	2.8	14 140	29.2	1763	33.3	22 579	7.6
Awaiting placement anytime	97	0.04	3680	7.6	434	8.2	4159	1.4
Median LOS (IQR)	4	2-6	9	4-19	12	6-28	4	2-8
Died in hospital	5013	2.1	6423	13.3	1093	20.7	12 529	4.2

Unless stated, numbers in right column are percentages.
SD standard deviation, IQR interquartile range.
*Measures number and severity of comorbidities [21].
**Measured using Escobar model [20] using covariate values at hospital admission.
***At any time during the hospitalization.
****Laboratory-based Acute Physiology Score; quantifies deviations of important laboratory tests from normal [20].

ISSN: 1471-2334