Skip to main content

Table 1 Characteristics of all subjects andusage of microbiota-targeted agents in secondary infection and non-secondary infection groups of H7N9 patients

From: An analysis of microbiota-targeted therapies in patients with avian influenza virus subtype H7N9 infection

Characteristics Secondary infection group Non-secondary infection group Healthy controls
(n = 11) (n = 14) (n = 25)
Median age (years) 64.5 48 58
Male:female (n) 9:2 8:6 17:8
Median hospital stay (days) 21.5 13 -a
Primary blood parameters at first follow-up:    
Mean WBC (SD, 109cells per liter) 8.0 (3.5) 4.6 (3.3) 5.7 (1.3)
Mean CRP (SD, mg per liter) 61.7 (72.3) 42.8 (53.2) -
ALT median (25th–75th percentile, units per liter) 38 (25–50) 44 (19.5–114) 16 (12.5–21)
Antimicrobial usage:    -
Cephalosporins (n) 7 9 -
Carbapenems (n) 6 1 -
β-Lactamase inhibitors and cephalosporins (n) 4 3 -
β-Lactamase inhibitors and penicillins (n) 9 5 -
Quinolones (n) 10 8 -
Macrolides (n) 4 1 -
Vancomycin (n) 5 0 -
Tigecycline (n) 4 0 -
Oxazolidinones (n) 3 0 -
Phosphonomycin (n) 1 1 -
Antifungalagents (n) 1 0 -
Micro-ecological-targeted agents    -
CBM588 (n) 9 11 -
Bacillussubtilis- and E. faecium-coated enteric capsules (n) 1 1 -
Lactulose (n) 4 0 -
Infection with    -
Canidia (n) 7 0 -
Klebsiella pneumoniae, n 6 0 -
Acinetobacter baumanii (n) 5 0 -
Pseudomonas (n) 5 0 -
Flavobacterium indologenes (n) 1 0 -
Staphylococcus (n) 2 0 -
Infections with mixed culture (n) 7 0 -
Diarrhea (n) 3 0 -
  1. Abbreviations: WBC white blood cell, SD standard deviation, CRP C-reactive Protein, ALT alanine aminotransferase, CBM588, Clostridium butyricum 588 strain MIYA-BM tablets.
  2. aNot applicable.