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Table 6 Examination of “high risk” adults (age > 15) for key risk factors (N (%))

From: Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda

  PTST- TSTC TST+ Comparison across all 3 groups Comparison of PTST- vs TSTC + TST+ Comparison of PTST- and TSTC vs TST+
Characteristics of household
Number of windows in house
Mean (SD) 3.48 (3.25) 3.10 (2.78) 1.93 (2.03) < 0.0005 0.056 < 0.0005
Number of rooms in house
Mean (SD) 4.26 (4.06) 3.87 (3.23) 2.77 (2.42) 0.002 0.096 < 0.0005
# People in household/room
Mean (SD) 8.22 (7.30) 7.30 (5.88) 5.99 (3.93) 0.198 0.259 0.030
Characteristics of index case
Presence of cavitary disease
No 12 (54.5%) 28 (42.4%) 155 (38.4%)    
Yes 10 (45.5%) 38 (57.6%) 249 (61.6%) 0.290 0.181 0.231
Baseline extent of disease on chest x-ray
Normal 3 (13.6%) 5 (7.6%) 13 (3.2%)    
Minimal 5 (22.7%) 7 (10.6%) 44 (10.9%)    
Moderate 7 (31.8%) 29 (43.9%) 145 (35.9%)    
Advanced 7 (31.8%) 25 (37.9%) 202 (50.0%) 0.069 0.085 0.033
  1. “High risk” defined as a score ≥ 6 out of 10 on risk score (based on Mandalakas et al. criteria).
  2. PTST- = Persistently negative tuberculin skin test; TSTC = Tuberculin skin test converter; TST + = tuberculin skin test positive at baseline.