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Table 6 Examination of “high risk” adults (age > 15) for key risk factors (N (%))

From: Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda

 

PTST-

TSTC

TST+

Comparison across all 3 groups

Comparison of PTST- vs TSTC + TST+

Comparison of PTST- and TSTC vs TST+

Characteristics of household

Number of windows in house

Mean (SD)

3.48 (3.25)

3.10 (2.78)

1.93 (2.03)

< 0.0005

0.056

< 0.0005

Number of rooms in house

Mean (SD)

4.26 (4.06)

3.87 (3.23)

2.77 (2.42)

0.002

0.096

< 0.0005

# People in household/room

Mean (SD)

8.22 (7.30)

7.30 (5.88)

5.99 (3.93)

0.198

0.259

0.030

Characteristics of index case

Presence of cavitary disease

No

12 (54.5%)

28 (42.4%)

155 (38.4%)

   

Yes

10 (45.5%)

38 (57.6%)

249 (61.6%)

0.290

0.181

0.231

Baseline extent of disease on chest x-ray

Normal

3 (13.6%)

5 (7.6%)

13 (3.2%)

   

Minimal

5 (22.7%)

7 (10.6%)

44 (10.9%)

   

Moderate

7 (31.8%)

29 (43.9%)

145 (35.9%)

   

Advanced

7 (31.8%)

25 (37.9%)

202 (50.0%)

0.069

0.085

0.033

  1. “High risk” defined as a score ≥ 6 out of 10 on risk score (based on Mandalakas et al. criteria).
  2. PTST- = Persistently negative tuberculin skin test; TSTC = Tuberculin skin test converter; TST + = tuberculin skin test positive at baseline.