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Table 2 Individual epidemiological measures

From: Clinical and epidemiological characteristics of individuals resistant to M. tuberculosis infection in a longitudinal TB household contact study in Kampala, Uganda

 

PTST-

TSTC

TST+

Total

Statistical comparison across 3 groups

Statistical comparison of PTST- vs. TSTC + TST+

Statistical comparison of PTST- + TSTC vs. TST+

Share bed with index case

No

122 (85.9%)

140 (83.3%)

698 (77.6%)

960 (79.3%)

   

Yes

20 (14.1%)

28 (16.7%)

202 (22.4%)

250 (20.7%)

   

All

142

168

900

1210

0.028

0.039

0.009

Share room with index case

No

65 (45.8%)

83 (49.4%)

297 (33.0%)

445 (36.8%)

   

Yes

77 (54.2%)

85 (50.6%)

603 (67.0%)

765 (63.2%)

   

All

142

168

900

1210

<0.0005*

<0.0005*

<0.0005*

Share meals with index case

No

14 (9.9%)

16 (9.5%)

65 (7.2%)

95 (7.9%)

   

Yes

128 (90.1%)

152 (90.5%)

835 (92.8%)

1115 (92.1%)

   

All

142

168

900

1210

0.380

0.344

0.166

Type of house (muzigo vs other)

Not Muzigo

75 (52.8%)

95 (56.9%)

397 (44.4%)

567 (47.1%)

   

Muzigo

67 (47.2%)

72 (43.1%)

497 (55.6%)

636 (52.9%)

   

All

142

167

894

1203

0.004

0.148

0.001*

Frequency of contact with index case

<1 day/wk

1 (0.7%)

2 (1.2%)

19 (2.1%)

22 (1.8%)

   

1-3 day

6 (4.2%)

7 (4.2%)

38 (4.2%)

51 (4.2%)

   

4-6 days

7 (4.9%)

5 (3.0%)

24 (2.7%)

36 (3.0%)

   

daily

129 (90.1%)

153 (91.1%)

816 (90.7%)

1097 (90.7%)

   

Total

142

167

897

1206

0.740

0.536

0.593

Time spent with index case (hours)

<1

3 (2.1%)

5 (3.0%)

19 (2.1%)

27 (2.3%)

   

2-6

17 (12.1%)

16 (9.5%)

78 (8.8%)

111 (9.3%)

   

7-12

70 (49.6%)

87 (51.8%)

511 (57.5%)

668 (55.8%)

   

13-18

29 (20.6%)

38 (22.6%)

162 (18.2%)

229 (19.1%)

   

>18

22 (15.6%)

22 (13.1%)

118 (13.3%)

162 (13.5%)

   

Total

141

168

888

1197

0.659

0.339

0.539

Number of windows in house

Mean (SD)

2.6 (2.773)

2.64 (2.475)

1.87 (2.056)

 

<0.0005*

< 0.0005*

0.029

Number of rooms in house

Mean (SD)

3.44 (3.183)

3.26 (2.541)

2.70 (2.383)

 

<0.0005*

< 0.0005*

0.041

# People in household/room

Mean

7.80 (5.235)

6.76 (4.129)

6.10 (3.672)

 

<0.0005*

< 0.0005*

< 0.0005*

Number of TB cases in home

Mean

1.67 (0.98)

1.66 (0.867)

1.61 (.896)

 

0.985

0.363

0.799

Relationship to index case

  

Spouse

6 (4.2%)

10 (6.0%)

122 (13.6%)

138 (11.4%)

   

Parent

3 (2.1%)

5 (3.0%)

48 (5.3%)

56 (4.6%)

   

Sibling

23 (16.2%)

22 (13.1%)

113 (12.6%)

158 (13.1%)

   

Avuncular

24 (16.9)

29 (17.3%)

128 (14.2%)

181 (15.0%)

   

Child

59 (41.5%)

66 (39.3%)

325 (36.1%)

450 (37.2%)

   

Grandparent/Child

3 (2.1%)

4 (2.4%)

18 (2.0%)

25 (2.1%)

   

Unrelated

21 (14.8%)

27 (16.1%)

126 (14.0%)

174 (14.4%)

   

Other relative

3 (2.1%)

5 (3.0%)

20 (2.2%)

28 (2.3%)

   

Total

142

168

900

1210

0.060

0.102

0.003

  1. PTST- = Persistently negative tuberculin skin test; TSTC = Tuberculin skin test converter; TST + = tuberculin skin test positive at baseline.
  2. *indicates P value that is significant after multiple testing correction.