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Table 1 Intervention parameters: vaccination coverage of 12-year olds, reduction in future HPV and intervention costs

From: Is expanding HPV vaccination programs to include school-aged boys likely to be value-for-money: a cost-utility analysis in a country with an existing school-girl program

Intervention Vaccination coverage Beta distribution for vaccination coverage Reduction in HPV infection for central estimate of vaccination coverage only (95% uncertainty interval) Vaccination costs (NZ$ 2011; SD as% of expected valued used for gamma distribution)
Females Males
HPV6/11 HPV16/18 HPV6/11 HPV16/18
Intervention 1G: Girls only program as per NZ in 2011 Māori: 56%; assumed SD = 2% alpha = 344, beta = 271 Māori: 75% (57% to 83%) Māori: 49% (41% to 59%) Māori: 75% (55% to 83%) Māori: 47% (41% to 53%) $760 (10%)
Non-Māori: 45%; assumed SD = 2% alpha = 278, beta =340 Non-Māori: 67% (48% to 76%) Non-Māori: 41% (33% to 50%) Non-Māori: 66% (47% to 74%) Non-Māori: 37% (32% to 43%) [($113 vaccine + $141 administrative) × 3]
Intervention 2G: Enhanced uptake as per Australia with school-only delivery (girls only) 73% (no variation by ethnicity or deprivation level); assumed SD = 5% alpha = 56.8, beta = 21.0 81% (64% to 88%) 63% (53% to 73%) 81% (65% to 88%) 61% (53% to 67%) $716 (10%) [($113 vaccine + $126
administrative) × 3]
Intervention 1G + B: Adding boys to 1G Māori: 56%; assumed SD = 2% alpha = 8.14, beta = 1.86 Māori: 77% (59% to 85%) Māori: 67% (53% to 79%) Māori: 78% (58% to 88%) Māori: 73% (63% to 83%) $760 (10%)
  Non-Māori: 45%; assumed SD = 2% alpha = 8.09, beta = 1.90 Non-Māori: 70% (50% to 79%) Non-Māori: 58% (45% to 71%) Non-Māori: 71% (51% to 80%) Non-Māori: 65% (54% to 75%) [($113 vaccine + $141 administrative) × 3]
Intervention 2G + B: Adding boys to 2G 73%; assumed SD = 5% alpha = 7.84, beta = 2.16 81% (67% to 89%) 78% (65% to 90%) 82% (68% to 89%) 85% (65% to 96%) $716 (10%)
[($113 vaccine + $126 administrative) × 3]
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