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Table 1 Analysis model inputs

From: Cost effectiveness of a pentavalent rotavirus vaccine in Oman

Parameter Base case value (Range for one-way sensitivity analysis) Source
Birth cohort 65500 Birth Registry DG-PL
   Deaths 6 (4.8,7.2) Al Awaidy 2009, Parashar 2004
   Hospitalizations 4279 (3423, 5135) Al Awaidy 2009
   ED Visits 3294 (2,635, 3,953) Al Awaidy 2009, Howidi 2012
   Office visits 14,838 (11870, 17,806) Al Awaidy 2009, Parashar 2003 &2006
   Average hospital length of stay 3 days Al Awaidy 2009
   Distribution of health care contacts by type   Al Awaidy 20091
Vaccine efficacy (assumed rate reduction) for complete series   
Deaths and hospitalizations 88% Vesikari et al. 2006
Office visits 86% Vesikari et al. 2006
Parental work loss   Howidi, 2012
Days of work loss for episodes requiring death/hospitalization 2 Assumption
Days of work loss for episodes requiring ED visits 1 Assumption
Days of works loss for episodes requiring office visits 0.50 Assumption
Days of works loss for episodes requiring no care 0.50 Assumption
Percentage of working parents who missed work for episodes involving deaths/hospitalizations 100% Assumption
Percentage of working parents who missed work for episodes involving outpatient visits and no care 100% Assumption
Vaccine Coverage 94%: 3 doses, 3%: 2 doses, 3%: 1 dose WHO
Health care and vaccination costs,OMR [USD]   
Hospital day 71 (57, 85) [184.6 (148.2, 221)] Al Awaidy 2009
ED visit 27 (21.6, 32.4) [70.2 (56.16,84.24)] Al Awaidy, 2009
Office visit 27 (21.6, 32.4) [70.2 (56.16,84.24)] Al Awaidy 2009
Day of missed work 11.40 [29.64]  
Direct non-medical care for hospitalizations or deaths 12.5 [32.5] Assumption
Direct non-medical care for ED visits 7.5 [19.5] Assumption
Direct non-medical outpatient visits and no care 7.5[19.5] Assumption
Price per dose 7.69 [19.994]  
Administration fee per dose 0 Assumption
QALY decrement per rotavirus episode 0.0058 (0.0022, 0.0133) Brisson et al. 2010
  1. ED = emergency department; OMR = Omani rial; USD = United States dollars; QALY = quality-adjusted life year; DG-PL = Omani Birth Registry Director General of Planning; WHO = World Health Organization.
  2. Exchange rate: 1 OMR = 2.60 USD.