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Table 2 Multivariate analysis of risk factors for suboptimal CD4 response

From: Predictors of suboptimal CD4 response among women achieving virologic suppression in a randomized antiretroviral treatment trial, Africa

Variable

 

Odds ratio (95% CI)

P-value for overall effect

Age

per 10 years increase

2.32 (1.60, 3.34)

<0.001

Baseline HIV-1 RNA

per 1 log10 copies/mL increase

0.46 (0.30, 0.71)

<0.001

Screening CD4

per 100 cells/μL) increase

0.66 (0.38,1.15)

0.14

Hepatitis B surf. antigen

Positive vs. Negative

2.86 (1.05, 7.77)

0.040

Enrollment site

Harare Zimbabwe1

1 (reference site)

 
 

Botswana

2.18 (0.60, 7.89)

0.005

 

Durban SA 2

2.96 (0.76, 11.57)

 
 

Eldoret Kenya

9.63 (3.01, 30.82)

 
 

Kericho Kenya

2.35 (0.63, 8.77)

 
 

Johannesburg

SA2 1.15 (0.20, 6.55)

 
 

Johannesburg

WITS3 SA2 2.97 (0.83,10.57)

 
 

Lilongwe Malawi

2.21 (0.55, 8.90)

 
 

Kampala Uganda

2.77 (0.75, 10.22)

 
 

Lusaka Zambia

5.05 (1.53, 16.67)

 
  1. 1Reference category 2South Africa 3University of Witwatersrand.