Table 1 Comparison of published cases of imquimod-induced vitiligo or vitiligo-like depigmentation in English literature
From: Induction of vitiligo after imiquimod treatment of condylomata acuminata
Case | Author (year) | Age (year)/ gender | Diagnosis | Site | Clinical presentation | Pathology | Family genetic history |
|---|---|---|---|---|---|---|---|
1 | Brown et al. 2005 [5] | 25/M | Vitiligo-like hypopigmentation | Scrotum | Multiple depigmented patches on the scrotum ranging from 3 mm to 2 cm | No | No report |
2 | Stefanaki et al. 2006 [6] | 32/M | Vitiligo | Dorsal surface of penis, scrotum, and pubic area | Vitiligo, slight repigmentation | No | Yes |
3 | Senel et al. 2007 [8] | 32 M | Vitiligo-like depigmentation | Glans penis, shaft of penis, and scrotum | Depigmented areas | No | No |
4 | Al-Dujaili et al. 2007 [7] | 21/M | Vitiligo | Penile shaft and scrotum | Depigmented patches | No | No report |
5 | Serrão et al. 2008 [9] | 26/M | Vitiligo-like depigmentation | Shaft of penis | Vitiligo-like depigmentation | No | No report |
6 | Zhang et al. 2011 [10] | 25/M | Vitiligo | Coronoid sulcus and corpus penis | Ivory-white patch nearly 4 × 2 cm | No | No report |
7 | Zhang et al. 2011 [10] | 22/M | Vitiligo | Penis | Depigmented patches with irregular pigmented edges | No | No report |
8 | Wang et al. 2013 [11] | 36/F | Vitiligo | Perineum and perianal | Depigmentation patches with clear demarcation lines | No | No |