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Table 2 Demographic and perinatal features in cases and controls

From: Invasive candidiasis in low birth weight preterm infants: risk factors, clinical course and outcome in a prospective multicenter study of cases and their matched controls

Features number (%) or mean ± SD or median (range) unless otherwise stated All cases All controls Significance P value Non-congenital cases Non-congenital controls Significance P value from matched analysis
N = 49 N = 90 N = 34 N = 62
Singleton 35 (71) 71 (79) 0.32 26 (77) 50 (81) 0.63
Vaginal delivery 29/49 (59) 50/89 (56) 0.73 16 (47) 31 (51) 0.72
Male 32 (65) 59 (66) 0.97 25 (74) 45 (73) 0.92
White 21/44 (48) 52/87 (60) 0.56 15/31 (48) 33/59 (56) 0.86
Black 7 (16) 13 (15) 1.00 5 (16) 10 (17.0) 0.99
Hispanic 4 (9) 5 (6) 0.92 3 (10) 5 (8) 0.97
Other 12 (27) 17 (19) 0.60 8 (26) 11 (19) 0.63
Mean birth weight (g) 748 ± 159 755 ± 146 0.80 790 ± 162 792 ± 151 0.93
Mean head circumference at birth (cm) 22.9 ± 1.6 23.3 ± 1.9 0.33 23.5 ± 1.6 23.5 ± 1.3 0.93
Mean length at birth (cm) 32.1 ± 2.2 32.9 ± 2.7 0.14 32.5 ± 2.3 33.0 ± 2.4 0.37
Median gestational age (weeks) 25 (23–30) 25.5 (23–30) 0.73 25.5 (23–30) 25.5 (23–30) 0.70
Respiratory distress syndrome 41 (84) 83 (92) 0.35 26 (77) 56 (90) 0.23
Gastrointestinal disorders other than NECa 2 (4) 1 (1) 0.23 2 (6) 1 (2) 0.26
NEC 12 (24) 8 (9) 0.008 12 (35) 6 (10) 0.01
PDA or other congenital heart diseaseb 37 (76) 63 (70) 0.67 27 (80) 42 (68) 0.25
Intrauterine growth retardation 3 (6) 4 (4) 1.00 3 (9) 4 (6) 1.00
Median age at enrolment (days) 14 (1–84) 14 (0–84) 1.00 20 (9–84) 16 (3–84) 0.89
Median time from admission to death or discharge) (days) 71 (3–492) 89 (1–165) 0.54 91 (3–492) 79 (1–142) 0.09
  1. Abbreviation: PDA, patent ductus arteriosus.
  2. aAll required gastrointestinal surgery and included imperforate anus and jejunal perforation.
  3. b36/37 cases and all 63 controls had only PDA.