| |
Fold change
|
|---|
|
SYMBOL
|
RSA infants
|
UK adults
|
|---|
|
CXCL10
|
3.2
|
6.5
|
|
ANKRD22
|
2.6
|
2.0
|
|
INDO
|
2.5
|
1.3
|
|
GBP5
|
2.5
|
2.2
|
|
ANKRD22
|
2.5
|
1.7
|
|
IDO1
|
2.4
|
1.4
|
|
FCGR1C
|
2.1
|
1.7
|
|
LOC400759
|
2.0
|
2.1
|
|
FAM26F
|
1.9
|
1.8
|
|
XRN1
|
1.7
|
1.0
|
|
PARP9
|
1.7
|
1.8
|
|
UBE2L6
|
1.6
|
1.6
|
|
SGK1
|
-1.6
|
1.1
|
|
CABC1
|
-1.6
|
-1.3
|
|
CARD17
|
1.6
|
1.2
|
|
CASP1
|
1.6
|
1.7
|
|
SGK1
|
-1.6
|
1.1
|
|
MRPL44
|
1.5
|
1.1
|
|
ZNF395
|
-1.5
|
-1.3
|
|
ETV7
|
1.5
|
1.0
|
|
CASP4
|
1.5
|
1.2
|
|
PCBP2
|
-1.5
|
-1.2
|
|
FAIM3
|
-1.5
|
-1.3
|
- South African infants: unstimulated whole blood taken 1 day post-vaccination. UK adults: unstimulated PBMC taken 2 days post-vaccination. All genes are differentially expressed between MVA85A and candin vaccinated infants (fdr < 0.05); genes in bold are also significantly different between day 0 and day 2 in UK adults vaccinated with MVA85A.
