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Table 3 Differentially expressed genes following Ag85A stimulation post-MVA85A vaccination

From: Inflammatory and myeloid-associated gene expression before and one day after infant vaccination with MVA85A correlates with induction of a T cell response

Vaccinated infants: day 28- day-7 Day 28 samples: vaccinated- placebo
SYMBOL logFC Fold change adj.P.Val SYMBOL logFC Fold change adj.P.Val
LOC400759 2.04 4.11 0.0047 LOC400759 2.71 6.55 0.012
GBP5 2.16 4.46 0.0079 STAT1 2.69 6.46 0.012
LOC730249 1.93 3.82 0.0079 STAT1 2.31 4.96 0.012
WARS 1.37 2.58 0.0079 CXCL10 3.41 10.64 0.015
ANKRD22 1.67 3.19 0.018 CCL8 4.02 16.21 0.027
GBP4 1.4 2.63 0.018 GBP4 2.19 4.55 0.027
WARS 1.25 2.38 0.018 CXCL9 1.95 3.86 0.027
TAP1 0.79 1.73 0.0234 STAT1 1.78 3.44 0.027
AIM2 1.05 2.07 0.0251 WARS 1.69 3.23 0.027
PSME2 0.72 1.65 0.0251 IFI35 1.49 2.8 0.027
CXCL9 1.63 3.09 0.0259 WARS 1.73 3.31 0.03
GBP1 1.9 3.72 0.0349 GBP1 2.86 7.28 0.031
STAT1 1.15 2.22 0.0354 PARP9 1.56 2.94 0.031
STAT1 1.32 2.49 0.0476 FBXO6 1.84 3.57 0.037
STAT1 0.92 1.89 0.0746 PARP9 1.46 2.75 0.051
GBP1 1.87 3.66 0.0911 PARP14 1.24 2.36 0.051
CD38 0.8 1.74 0.0925 PSME2 1.12 2.17 0.051
CXCL10 2.3 4.92 0.1295 GBP5 2.65 6.3 0.058
LAP3 1.13 2.19 0.1295 EPSTI1 1.51 2.85 0.058
CEACAM1 0.96 1.95 0.1412 GBP1 3.01 8.05 0.062
PARP14 0.71 1.63 0.1412 IFNG 2.17 4.51 0.062
IFNG 1.67 3.19 0.1599 P2RX7 1.77 3.42 0.062
     SAMD9L 1.37 2.58 0.062
     PTER 1.18 2.27 0.062
     UBE2L6 1.14 2.21 0.076
     IFIT3 2.35 5.09 0.08
     SNHG5 -1.17 -2.25 0.08
     LOC730249 2.32 5 0.082
     PLA2G4C 1.39 2.61 0.082
  1. PBMC stimulated for 12 hours with Ag85A peptide pools, genes identified using the R package limma. Genes in italics have an adjusted p value 0.05 < p < 0.2).