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Table 1 Patient and hospital characteristics

From: Hospital days, hospitalization costs, and inpatient mortality among patients with mucormycosis: a retrospective analysis of US hospital discharge data

 

Before propensity-score matching1

After propensity-score matching1

Characteristic

Cases

Non-Cases

P-value3

Cases

Non-Cases

P-value3

N (unweighted)

1,120

29,759,178

 

1,084

3,252

 

N (weighted)

5,515

146,295,097

 

5,346

15,999

 

Sex (%)

  

< 0.001

  

0.7550

  Female

39.6%

53.2%

 

40.5%

41.0%

 

  Male

60.4%

46.6%

 

59.5%

59.0%

 

  Unknown

0.0%

0.3%

 

-

-

 

Age (%)

      

  Mean (SD)

49.5 (20.0)

59.7 (21.4)

< 0.001

49.6 (19.9)

49.7 (19.9)

0.9074

  < 44

33.1%

21.4%

 

33.0%

32.6%

 

  45 to 64

43.6%

31.0%

 

43.5%

43.7%

 

  ≥ 65

23.4%

47.6%

 

23.5%

23.7%

 

Race (%)

  

< 0.001

  

0.8093

  White

53.6%

54.9%

 

53.3%

55.9%

 

  African-American

10.5%

10.7%

 

10.7%

10.0%

 

  Hispanic

13.5%

7.8%

 

13.6%

13.3%

 

  Other/Unknown

22.4%

26.5%

 

22.4%

20.8%

 

Primary expected payer (%)

  

< 0.001

  

0.7473

  Medicare

33.7%

51.1%

 

33.6%

31.2%

 

  Medicaid

21.0%

11.2%

 

20.8%

20.8%

 

  Private

37.4%

29.4%

 

37.8%

39.9%

 

  Other/Unknown

8.0%

8.3%

 

7.8%

8.1%

 

High-risk conditions2 (%)

  

< 0.001

  

0.5281

  (A) Severely immunocompromised

49.7%

6.2%

 

49.1%

49.0%

 

  (C) Mildly/moderately immunocompromised

25.1%

45.5%

 

25.5%

23.8%

 

  (B) Critically ill

20.0%

20.3%

 

20.0%

21.8%

 

  (D) Major surgery or Pneumonia

5.3%

27.9%

 

5.5%

5.4%

 

Number of Elixhauser comorbidities

      

  Mean (SD)

2.7 (1.8)

2.4 (1.8)

< 0.001

2.7 (1.8)

2.6 (1.7)

0.0340

  Median (IQR)

2 (1–4)

2 (1–3)

 

3 (1–4)

2 (1–4)

 

Number of listed diagnoses

      

  Mean (SD)

12.1 (4.8)

8.3 (4.3)

< 0.001

12.2 (4.8)

9.2 (4.6)

<0.001

  Median (IQR)

11 (9–15)

8 (5–10)

 

11 (9–15)

9 (6–12)

 

Number of listed procedures

      

  Mean (SD)

5.3 (4.5)

2 (2.3)

< 0.001

5.3 (4.5)

2.5 (2.8)

<0.001

  Median (IQR)

5 (2–8)

1 (0–3)

 

5 (2–8)

2 (1–3)

 

Abdominal procedures or surgeries4 (%)

5.5%

12.0%

< 0.001

5.4%

4.9%

0.5314

Geographic Region (%)

  

< 0.001

  

0.2629

  Northeast

15.4%

19.5%

 

15.4%

16.7%

 

  Midwest

18.5%

23.6%

 

18.5%

16.1%

 

  West

31.9%

18.2%

 

32.4%

33.3%

 

  South

34.2%

38.7%

 

33.6%

33.9%

 

Hospital location (%)

  

< 0.001

  

0.6274

  Urban

95.9%

86.9%

 

96.8%

97.0%

 

  Rural

3.1%

12.7%

 

3.2%

3.0%

 

  Missing

1.0%

0.5%

 

-

-

 

Hospital teaching status (%)

  

< 0.001

  

0.4091

  Teaching

72.6%

46.8%

 

73.1%

74.3%

 

  Non-teaching

26.4%

52.8%

 

26.9%

25.7%

 

  Missing

1.0%

0.5%

 

-

-

 

Hospital bed size (%)

  

< 0.001

  

0.0668

  Small (1–49 beds)

7.7%

12.2%

 

7.8%

6.6%

 

  Medium (50–99 beds)

15.2%

23.7%

 

15.5%

13.9%

 

  Large (≥ 100 beds)

76.1%

63.6%

 

76.6%

79.5%

 

  Missing

1.0%

0.5%

 

-

-

 
  1. Source: HCUP 2003–2010.
  2. [1] Non-mucormycosis hospitalizations from hospitals with at least one mucormycosis patient were matched 3:1 to mucormycosis hospitalizations using a greedy 8 to 1 digit matching algorithm. This algorithm first matches on 8 digits of propensity score and then subsequently on 7 and so on.
  3. [2] All high-risk groups were mutually exclusive; ordered here by prevalence post-matching. Severely immunocompromised (A) conditions include leukemia/lymphoma/HSCT/BMT, chemotherapy, other immune disorders, solid organ transplant or long-term steroid use. Critically ill (B) conditions include trauma, septicemia, bacteremia, necrotizing fasciitis, intracranial hemorrhage and mechanical ventilation for 96+ hours. Mildly/moderately immunocompromised (C) conditions include ESRD/hemodialysis, lupus, malignant solid tumors, diabetic ketoacidosis, blood disorders, and diabetes. Major surgery or pneumonia (D) includes selected thoracic, cardiac, vascular, abdominal, peripheral, urology, and neurology surgeries, other major procedures, and pneumonia.
  4. [3] Significance was tested for proportions using the Rao-Scott Chi-Square Test. Continuous measures were tested using an independent sample t-test.
  5. [4] Abdominal procedures/surgeries include: ICD-9-CM 43.XX-50.XX, 51.2X, and 52.XX-54.XX, excluding 43.1X, 43.4X, 43.9X, 44.1X, 44.22, 44.43, 44.44, 44.49, 44.91, 45.1X-45.3X, 46.32, 46.32, 46.39, 48.2X, 48.3X, 50.1X, 50.9X, 52.0X, 52.1X, 52.4X, 52.9X, 54.22-54.29, 54.9X.