Laboratory results iCDI onset
| | | |
Low albumin
|
50 (12)
|
548 (15)
|
0.84 (0.63 – 1.13)
|
Low WBC
|
64 (15)
|
635 (17)
|
0.99 (0.82 – 1.20)
|
High WBC
|
247 (58)
|
2027 (54)
|
1.23 (1.01 – 1.49)
|
Low hemoglobin
|
218 (51)
|
1985 (53)
|
0.96 (0.79 – 1.16)
|
High creatinine
|
99 (23)
|
862 (23)
|
1.08 (0.86 – 1.35)
|
Relevant medications present at iCDI onset
| | | |
Any antimicrobial
|
314 (74)
|
2729 (72)
|
1.10 (0.88 – 1.36)
|
Low risk antimicrobial(s)a
|
95 (22)
|
1058 (28)
|
0.76 (0.60 – 0.95)
|
High risk antimicrobial(s)b
|
174 (41)
|
1490 (40)
|
1.07 (0.88 – 1.29)
|
Fluoroquinolone
|
120 (28)
|
861 (23)
|
1.29 (1.05 – 1.60)
|
IV vancomycin
|
130 (31)
|
1321 (35)
|
0.86 (0.70 – 1.05)
|
Gastric acid suppressor, any
|
310 (73)
|
2850 (76)
|
0.91 (0.73 – 1.12)
|
New gastric acid suppressor
|
54 (13)
|
255 (7)
|
1.87 (1.41 – 2.49)
|
Relevant medications received following iCDI onset
| | | |
Any antibiotic first dose after CDI
|
278 (65)
|
1622 (43)
|
2.47 (2.02 – 3.02)
|
Low risk antimicrobial(s) first dose after CDIa
|
141 (33)
|
710 (19)
|
2.09 (1.71 – 2.56)
|
High risk antimicrobial(s) first dose after CDIb
|
150 (35)
|
714 (19)
|
2.30 (1.89 – 2.81)
|
Fluoroquinolone first dose after CDI
|
124 (29)
|
703 (19)
|
1.69 (1.37 – 2.09)
|
IV vancomycin first dose after CDI
|
115 (27)
|
337 (12)
|
2.61 (2.11 – 3.23)
|
Initial CDI treatment
| | | |
Metronidazole alone
|
323 (76)
|
2841 (75)
|
Reference
|
Oral vancomycin alone
|
16 (4)
|
104 (3)
|
1.32(0.80 – 2.18)
|
Metronidazole and oral vancomycin
|
86 (20)
|
829 (22)
|
0.95 (0.75 – 1.20)
|