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Table 2 Characteristics, clinical signs, case classifications and rubella antibodies among seven confirmed or potential CRS cases

From: Identification of congenital rubella syndrome in Sudan

Cases

Age (months)

Clinical signs

WHO definitions for CRS cases

IgM (OF)

IgM (DBS)

IgG (DBS)

History of Maternal rash

Case 1

3

Glaucoma

Congenital rubella infection

+

+

NT

No

Case 2

9

Cataract, pigmentary retinopathy, microphthalmia

Laboratory-confirmed CRS

+

+

+

No

Case 3

6

Cataract, CHD (VSD), splenomegaly, jaundice

Clinically-confirmed CRS#

+

Yes

Case 4

6

Glaucoma, CHD (PDA, ASD)

Clinically-confirmed CRS#

±

+

No

Case 5

6

Pigmentary retinopathy

Suspected CRS#

+

No

Case 6

6

Cataract

Suspected CRS#

+

No

Case 7

12

Micropthalmia, purpura

Suspected CRS#

+

No

  1. ASD = atreial septal defect; CHD = congenital heart disease; NT = Not Tested; PDA = Patent ductus arteriosus; VSD = Ventricular septal defect; # = potential CRS case.