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Table 2 Characteristics of the 218 HIV-TB co-infected patients divided by initiation timing of HAART*

From: The impact of HAART initiation timing on HIV-TB co-infected patients, a retrospective cohort study

 

HAART initiation timing during anti-TB therapy

 

No HAART (n = 36)

0–15 days (n = 110)

16–30 days (n = 34)

31–60 days (n = 19)

>60 days (n = 19)

Age (yrs) at first TB diagnosis, median [IQR]

38.8 [32.0–49.6]

36.8 [31.8–43.6]

35.5 [31.2–46.7]

36.6 [33.7–45.1]

40.4 [29.5–61.3]

Male

31 (86.1%)

107 (97.3%)

33 (97.1%)

18 (94.7%)

17 (89.5%)

Female

5 (13.9%)

3 (2.7%)

1 (2.9%)

1 (5.3%)

2 (10.5%)

CD4 count(/mm3) at TB diagnosis, median [IQR]$

69 [17–370]

37 [16–87]

34 [14–62]

68 [23–134]

36 [17–94]

  ≤50

14 (38.9%)

68 (62.4%)

26 (74.3%)

8 (42.15%)

11 (57.9%)

  51–100

7 (19.4%)

18 (16.4%)

2 (5.9%)

5 (26.3%)

4 (21.1%)

  101–200

5 (13.9%)

11 (10.1%)

3 (8.6%)

4 (21.1%)

1 (5.3%)

  ≥200

10 (30.8%)

13 (11.9%)

3 (8.6%)

2 (10.5%)

3 (15.8%)

Localization of tuberculosis

     

  Pulmonary

16 (44.4%)

31 (28.5%)

15 (42.9%)

6 (31.6%)

7 (36.8%)

  PTB+ extra-pulmonary

19 (52.8%)

72 (65.5%)

19 (55.9%)

6 (31.6%)

12 (63.2%)

  Extra-pulmonary

1 (2.8%)

7 (6.4%)

0

7 (36.8%)

0

Laboratory findings

     

  Positive AFS smear ± positive MTB Culture

27 (75.0%)

85 (78.0%)

29 (82.9%)

13 (68.4%)

12 (63.2%)

  Positive MTB culture only

9(25.0%)

25(22.7%)

5(14.7%)

6(31.6%)

7(36.8%)

HBV(+)#$

6(16.7%)

22(20.2%)

1(2.9%)

4(21.1%)

3(15.8%)

HCV(+)#$

9(25.0%)

11(10.1%)

3(8.6%)

1(5.3%)

1(5.3%)

IRIS$

–

41(37.3%)

12(35.3%)

2(10.5%)

2(10.5%)

Death$

23(63.9%)

19(17.3%)

5(14.7%)

0

5(26.3%)

TB-related death$

19(52.8%)

15(13.6%)

2(5.9%)

0

3(15.8%)

  1. Data are presented as n (% of the category) unless otherwise indicated.
  2. Abbreviations: IQR interquartile range, PTB pulmonary tuberculosis. AFS acid-fast stain, MTB Mycobacterium tuberculosis, IRIS Immune reconstitution inflammatory syndrome, HBV hepatitis B virus infection, HCV hepatitis C virus infection.
  3. *Only included cases with available CD4+ lymphocyte count.
  4. #Only 153 and 141 patients had available HBV and HCV examination results respectively.
  5. $ p <0.01.