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Table 2 Expression patterns of selected biomarkers in 2011 follow-up samples compared to 2008 Chagasic patients treated with nifurtimox (Upward arrow: up-regulated; Downward arrow: down-regulated)

From: Serum biomarkers predictive of cure in Chagas disease patients after nifurtimox treatment

Nfx days Sample Lab ID 9.3 kDa 13.6 kDa 24.7 kDa 28.1 kDa 28.9 kDa 2008 ELISA OD 2011 ELISA OD 2011 ELISA 2011 PCR 2011 RT-PCR Cured (C) Not Cured (NC)
60 54 0.62 0.62 + - - C
60 56 2.53 2.02 + - - C
60 57 0.41 0.50 + - - C
60 59 2.37 2.17 + - - C
60 60 2.80 2.57 + - - NC
60 62 2.55 2.11 + - - NC
60 65 0.79 0.61 + - - NC
60 68 1.88 1.53 + - - NC
60 69 1.84 1.75 + - - NC
60 70 1.11 1.23 + - - NC
60 71 1.64 1.19 + - + NC
60 72 1.47 1.67 + - - C
60 77 2.16 1.58 + - - C
60 84 2.94 2.49 + - - C
60 85 1.76 2.11 + - - NC
60 86 2.18 2.25 + - - NC
60 87 1.95 1.89 + - - C
60 91 2.16 1.83 + - - NC
60 94 2.07 1.93 + - - C
60 97 2.26 1.85 + - - NC
60 99 1.69 1.25 + - - C
60 100 2.17 1.79 + - - C
60 102 2.61 1.31 + - - C
60 103 2.56 2.28 + - - NC
60 104 2.78 1.97 + - - C
58 64 2.55 2.27 + - - C
47 67 1.83 1.90 + - - C
31 58 2.28 1.91 + - - NC
21 80 2.42 1.78 + - - C
21 81 2.16 1.70 + - - NC
21 88 2.02 1.64 + - - NC
19 96 1.99 2.42 + - - NC
16 90 1.44 1.02 + - - NC
14 95 1.13 2.24 + - - NC
10 66 2.35 1.92 + - - NC
10 73 2.21 2.00 + - - NC
2 55 2.65 2.82 + - - NC
  1. ELISA cut-off: 0.4.