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Table 2 Separate and joint effects of the preventive exposures “Influenza vaccination” and “OFC” on the risk of ILI after recoding and results of analyses of interaction

From: Do the omeprazole family compounds exert a protective effect against influenza-like illness?

Odds Ratios representing separate effects

OR (95% CI)

Non-OFC users

4.38 (2.54 – 7.53)

Users of OFC

1 (reference category)

Not Vaccinated

3.8 (2.15 – 6.71)

Vaccinated

1 (reference category)

Odds Ratios representing joint effects

 

OR11 non-OFC users and unvaccinated

5.75 (2.71 – 12.22)*

OR10 non-OFC users but vaccinated

1.48 (0.64 – 3.40)

OR01 users of OFC but unvaccinated

0.92 (0.33 – 2.53)

OR00 users of OFC and vaccinated

1 (reference category)

Measure of effect of interaction on additive scale

 

RERI

4.34 (1.46 - 7.26)

  1. *Observed OR = 5.75, while expected OR in the absence of interaction on an additive scale was 1.40, calculated as [(1.48 – 1) + (0.92 – 1) + 1], where 1.48 = OR non-OFC users but vaccinated and 0.92 = OR users of OFC but unvaccinated.