Skip to main content
Figure 1 | BMC Infectious Diseases

Figure 1

From: Prevention of Clostridium difficilespore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam

Figure 1

Stacked bar graph showing the number of vegetative cells and spores in colonies grown for 48 h and 96 h on TY agar without antibiotics (No ATB) or with 0.5x MIC of TIGE, TZP, CIP, VAN, or MTZ. The values of spore counts (dark grey bars) are stacked on top of the vegetative cell counts (lower light grey bars). The percentage of spores formed in the presence or absence of antibiotics was also calculated for each condition and compared by one-way ANOVA. When the percentage of spores was significantly lower compared to the control. For simplicity, only the % spores for the controls and the significantly different conditions are indicated above the corresponding bars. Boxed values above some of the bars represent the % spores calculated using a spore recovery assay on agar plate after ethanol shock. Values represent means ± standard error of the mean of 3 independent experiments (mean of 5 microscopy images/experiment). Statistical significance: * = p < 0.05, ** = p < 0.01, *** = p < 0.001 and **** = p < 0.0001.

Back to article page