Skip to main content

Table 2 Susceptibility of the infectious agents found in 268 samples of ascitic fluid to different antimicrobials during the period 2010-2011

From: Evolving epidemiology and antimicrobial resistance in spontaneous bacterial peritonitis: a two-year observational study

 

Total (n = 268)

After exclusion of coagulase negative staphylococci (n = 195)

Non-nosocomial episodes (n = 109)

Nosocomial episodes (n = 159)

P1

SBP (n = 57)

Bacterascites (n = 140)

P 2

Amoxicillin

33.2%

45.6%

40.4%

28.3%

0.04

40.4%

33.3%

0.37

Amoxicillin + clavulanate

42.5%

53.3%

50.5%

38.1%

0.02

43.9%

44.3%

0.96

Broad-spectrum penicillin

35.4%

48.7%

38.5%

33.3%

0.38

40.4%

39.3%

0.89

Broad-spectrum penicillin + beta lactamase inhibitor

48.1%

64.1%

51.4%

45.9%

0.38

47.4%

50.7%

0.67

Third-generation cephalosporin

39.2%

39.0%

55.0%

28.3%

<0.0001

33.3%

42.1%

0.25

Fluoroquinolone

46.6%

46.7%

57.8%

39.0%

0.002

38.6%

47.1%

0.27

Aminoglycoside

50.0%

47.2%

56.9%

45.3%

0.06

47.4%

52.9%

0.48

Cotrimoxazole

42.2%

38.4%

53.2%

34.6%

0.002

29.8%

45.7%

0.04

Glycopeptide

57.8%

45.6%

60.6%

56.0%

0.45

50.9%

66.5%

0.04

  1. Percentages indicate the in vitro antimicrobial efficacy on the infectious agent (s) isolated in positive ascitic fluid cultures.
  2. (intermediate strains were considered non-susceptible).
  3. 1comparison between non-nosocomial and nosocomial episodes.
  4. 2comparison between SBP and bacterascites.