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Table 2 Susceptibility of the infectious agents found in 268 samples of ascitic fluid to different antimicrobials during the period 2010-2011

From: Evolving epidemiology and antimicrobial resistance in spontaneous bacterial peritonitis: a two-year observational study

  Total (n = 268) After exclusion of coagulase negative staphylococci (n = 195) Non-nosocomial episodes (n = 109) Nosocomial episodes (n = 159) P1 SBP (n = 57) Bacterascites (n = 140) P 2
Amoxicillin 33.2% 45.6% 40.4% 28.3% 0.04 40.4% 33.3% 0.37
Amoxicillin + clavulanate 42.5% 53.3% 50.5% 38.1% 0.02 43.9% 44.3% 0.96
Broad-spectrum penicillin 35.4% 48.7% 38.5% 33.3% 0.38 40.4% 39.3% 0.89
Broad-spectrum penicillin + beta lactamase inhibitor 48.1% 64.1% 51.4% 45.9% 0.38 47.4% 50.7% 0.67
Third-generation cephalosporin 39.2% 39.0% 55.0% 28.3% <0.0001 33.3% 42.1% 0.25
Fluoroquinolone 46.6% 46.7% 57.8% 39.0% 0.002 38.6% 47.1% 0.27
Aminoglycoside 50.0% 47.2% 56.9% 45.3% 0.06 47.4% 52.9% 0.48
Cotrimoxazole 42.2% 38.4% 53.2% 34.6% 0.002 29.8% 45.7% 0.04
Glycopeptide 57.8% 45.6% 60.6% 56.0% 0.45 50.9% 66.5% 0.04
  1. Percentages indicate the in vitro antimicrobial efficacy on the infectious agent (s) isolated in positive ascitic fluid cultures.
  2. (intermediate strains were considered non-susceptible).
  3. 1comparison between non-nosocomial and nosocomial episodes.
  4. 2comparison between SBP and bacterascites.