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Table 1 Distribution of the main infectious agents isolated in 268 ascitic fluid samples during the period 20102011

From: Evolving epidemiology and antimicrobial resistance in spontaneous bacterial peritonitis: a two-year observational study

  Total (n = 268) (n,%) Ascitic neutrophil count (median, IQR) Non-nosocomial episodes (n = 109) (n,%) Nosocomial episodes (n = 159) (n,%) p1 SBP (n = 57) (n,%) Bacterascites (n = 140) (n,%) p2 With FQ prophylaxis (n = 27) (n,%) Without FQ prophylaxis (n = 241) (n,%) p3
Streptococcus (other than S. pneumoniae) 33 (12.3%) 70 (21–150) 17 (15.6%) 16 (10.1%) 0.18 5 (8.8%) 18 (12.9%) 0.42 2 (7.4%) 31 (31.9%) 0.41
Streptococcus pneumoniae 4 (1.5%) 955 (200–1710) 4 (3.7%) 0 (0.0%) 0.01 1 (1.8%) 1 (0.7%) 0.51 0 (0.0%) 4 (1.7%) 0.50
Enterococcus sp. 65 (24 .3%) 75 (25–565) 15 (13.8%) 50 (31.4%) 0.0009 13 (22.8%) 31 (22.1%) 0.92 13 (48.1%) 52 (21.6%) 0.02
Staphylococcus aureus 7 (2.6%) 392 (18–815) 6 (5.5%) 1 (0.6%) 0.01 0 (0.0%) 0 (0.0%) - 1 (3.7%) 6 (2.5%) 0.71
Coagulase negative Staphylococcus 73 (27.2%) 63 (8–155,5) 25 (22.9%) 48 (30.2%) 0.19 13 (22.8%) 47 (33.6%) 0.14 4 (14.8%) 69 (28.6%) 0.13
Gram positive cocci 174 (64.9%) 77 (10–310) 67 (61.5%) 107 (67.3%) 0.33 32 (56.1%) 91 (65.0%) 0.24 20 (74.7%) 154 (63.9%) 0.29
Escherichia coli 48 (17.9%) 129 (86–830) 20 (18.3%) 28 (17.6%) 0.88 15 (26.3%) 21 (15.0%) 0.06 3 (11.1%) 45 (18.7%) 0.33
Klebsiella sp.Enterobacter sp. Serratia sp. 29 (10.8%) 92 (58–549) 10 (9.2%) 19 (11.9%) 0.47 5 (8.8%) 10 (7.1%) 0.70 6 (22.2%) 23 (9.5%) 0.04
Pseudomonas sp. 9 (3.4%) 59 (44–670) 0 (0.0%) 9 (5.7%) 0.01 0 (0.0%) 5 (3.6%) 0.15 0 (0.0%) 9 (3.7%) 0.31
Gram negative rods 91 (34.0%) 100 (66–660) 32 (29.4%) 59 (37.1%) 0.18 23 (40.4%) 39 (27.9%) 0.09 9 (33.3%) 82 (34.0%) 0.94
Anaerobes 11 (4.1%) 112 (12–500) 8 (7.3%) 3 (1.9%) 0.03 2 (3.5%) 4 (2.9%) 0.81 0 (0.0%) 11 (4.6%) 0.26
Fungi 7 (2.6%) 52 (30–55) 2 (1.8%) 5 (3.1%) 0.51 0 (0.0%) 3 (2.1%) 0.27 0 (0.0%) 7 (2.9%) 0.37
  1. Not all the infectious agents are listed in this table. Since several agents were isolated in the same sample of ascitic fluid, the total may exceed 100%.
  2. 1comparison between non-nosocomial and nosocomial episodes.
  3. 2comparison between SBP and bacterascites.
  4. 3comparison between episodes with and without fluoroquinolone (norfloxacine) prophylaxis.