Incidence and etiology of hemolytic-uremic syndrome in children in Norway, 1999–2008 – a retrospective study of hospital records to assess the sensitivity of surveillance

BMC Infectious Diseases

Table 2 Epidemiology of HUS in children in Norway between 1999 and 2008

Type of HUS	STEC-HUS	Probable STEC-HUS	Total D+HUS			D-HUS		All HUS
Measure	Cases (N)	Cases (N)	N	%	IR	N	%	N	%	IR
Age	Cases (N)	Cases (N)	N	%	IR	N	%	N	%	IR
0-4 y	19	11	30	79	1.0	8	89	38	81	1.3
0 y	2	1	3	8	0.5	2	22	5	11	0.9
1 y	7	5	12	32	2.1	4	44	16	34	2.7
2 y	5	3	8	21	1.4	0	0	8	17	1.4
3 y	0	2	2	5	0.3	0	0	2	4	0.3
4 y	5	0	5	13	0.8	2	22	7	15	1.2
5-9 y	3	3	6	16	0.2	1	11	7	15	0.2
10-15 y	1	1	2	5	<0.1	0	0	2	4	<0.1
Total	23	15	38	100	0.4	9	100	47	100	0.5

Age-specific distribution (in number), proportion (in percentage) and incidence rate (IR; in average annual incidence rate in cases per 100,000 children) for diarrhea-associated (D⁺HUS), with and without laboratory identified STEC infection (probable STEC-HUS) and the two combined, non-diarrhea-associated (D⁻HUS) and all of the cases of hemolytic-uremic syndrome (all HUS) in children in Norway, 1999–2008 (N = 47).