TY - JOUR AU - Jenssen, Gaute Reier AU - Hovland, Eirik AU - Bjerre, Anna AU - Bangstad, Hans-Jacob AU - Nygard, Karin AU - Vold, Line PY - 2014 DA - 2014/05/16 TI - Incidence and etiology of hemolytic-uremic syndrome in children in Norway, 1999–2008 – a retrospective study of hospital records to assess the sensitivity of surveillance JO - BMC Infectious Diseases SP - 265 VL - 14 IS - 1 AB - Public awareness of hemolytic-uremic syndrome (HUS), especially related to Shiga toxin-producing Escherichia coli (STEC), has increased in Europe in recent years; accentuated in Norway by a national outbreak in 2006 and in a European context especially by the 2011 outbreak originating in Germany. As STEC surveillance is difficult due to diagnostic challenges in detecting non-O157 infections, surveillance of HUS can be used to indicate the burden of STEC infection. Until 2006, notification of HUS to the Norwegian Communicable Disease Surveillance System (MSIS) was based on microbiologically confirmed infection with enterohemorrhagic Escherichia coli (EHEC), humanpathogenic STEC. In 2006, diarrhea-associated HUS (D+HUS) was made notifiable based on clinical criteria alone. The incidence and etiology of HUS in children in Norway has not previously been described. SN - 1471-2334 UR - https://doi.org/10.1186/1471-2334-14-265 DO - 10.1186/1471-2334-14-265 ID - Jenssen2014 ER -