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Table 1 Protection level induced by immunization with DNA-Sm14 or DNA-Sm14/DNA-Hsp65 48 days post infection with S. mansoni

From: Combined immunization using DNA-Sm14 and DNA-Hsp65 increases CD8+ memory T cells, reduces chronic pathology and decreases egg viability during Schistosoma mansoniinfection

Experiment Groups Worm Burden (mean) ± SEM n Protection
1 Control 19.86 1.405 7 -
1 DNA-Sm14 13.00* 1.024 7 34.5%a
1 DNA-Sm14/DNA-Hsp65 16.83 0.749 6 15.3%a
2 Control 18.29 0.746 7 -
2 DNA-Sm14 13.13* 1.231 8 28.2%a
2 DNA-Sm14/DNA-Hsp65 16.00 1.291 7 12.5%a
  1. *Significant reduction in worm burden recovery compared to control group in each experiment. p < 0.05.
  2. aWorm burden reduction compared to Control group in each experiment.