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Table 1 Protection level induced by immunization with DNA-Sm14 or DNA-Sm14/DNA-Hsp65 48 days post infection with S. mansoni

From: Combined immunization using DNA-Sm14 and DNA-Hsp65 increases CD8+ memory T cells, reduces chronic pathology and decreases egg viability during Schistosoma mansoniinfection

Experiment

Groups

Worm Burden (mean)

± SEM

n

Protection

1

Control

19.86

1.405

7

-

1

DNA-Sm14

13.00*

1.024

7

34.5%a

1

DNA-Sm14/DNA-Hsp65

16.83

0.749

6

15.3%a

2

Control

18.29

0.746

7

-

2

DNA-Sm14

13.13*

1.231

8

28.2%a

2

DNA-Sm14/DNA-Hsp65

16.00

1.291

7

12.5%a

  1. *Significant reduction in worm burden recovery compared to control group in each experiment. p < 0.05.
  2. aWorm burden reduction compared to Control group in each experiment.
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BMC Infectious Diseases

ISSN: 1471-2334

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