Table 2 Antibiotic resistance of ESC-resistant and susceptible Shigella isolates
Antibiotic | Number of isolates resistant to antibiotics (%) | ESC-resistant S. flexnerivs ESC-resistant S. sonnei (pvalue) | ||||||
|---|---|---|---|---|---|---|---|---|
Total (n = 356) | S. flexneri( n = 112) | S. sonnei(n = 244) |  | |||||
ESC-resistant (n = 58) | Cefotaxime susceptible (n = 54) | ESC-resistant vs cefotaxime susceptible (pvalue) | ESC-resistant (n = 140) | Cefotaxime susceptible (n = 104) | ESC-resistant vs cefotaxime susceptible (pvalue) | |||
AMP | 348 (97.8) | 58 (100) | 51(94.4) | 0.069 | 140(100) | 99(95.2) | 0.009 | NA |
PIP | 298 (83.7) | 58(100) | 46(85.2) | 0.002 | 140(100) | 54 (51.9) | <0.001 | NA |
SAM | 136 (38.2) | 56(96.6) | 46(85.2) | 0.035 | 34(24.3) | 0 (0.0) | <0.001 | <0.001 |
TZP | 1 (0.3) | 1 (1.7) | 0 (0.0) | 3.332 | 0 (0.0) | 0 (0.0) | NA | 0.119 |
CAZ | 59 (16.6) | 34(58.6) | 0 (0.0) | <0.001 | 25(17.9) | 0 (0.0) | <0.001 | <0.001 |
FEP | 66 (18.5) | 34(58.6) | 0 (0.0) | <0.001 | 32(22.9) | 0 (0.0) | <0.001 | <0.001 |
FOX | 8 (2.2) | 3 (5.2) | 0 (0.0) | 0.090 | 5 (3.6) | 0 (0.0) | 0.056 | 0.618 |
IPM | 0(0.0) | 0(0) | 0 (0.0) | NA | 0 (0.0) | 0 (0.0) | NA | NA |
SXT | 304 (85.4) | 43(74.1) | 25(46.3) | 0.003 | 135(96.4) | 101(97.1) | 0.766 | <0.001 |
CIP | 86 (24.2) | 43 (74.1) | 39 (72.2) | 0.819 | 3 (2.1) | 1 (1.0) | 0.485 | <0.001 |
LEV | 57 (16.0) | 31(53.4) | 20(37.0) | 0.081 | 3 (2.1) | 3 (2.9) | 0.692 | <0.001 |
β-lactam antibiotic + SXT + CIP or LEV | 69 (19.4) | 36 (62.1) | 23 (42.6) | 0.039 | 6 (4.3) | 4 (3.8) | 0.864 | <0.001 |