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Table 2 Antibiotic resistance of ESC-resistant and susceptible Shigella isolates

From: Epidemic and virulence characteristic of Shigella spp. with extended-spectrum cephalosporin resistance in Xiaoshan District, Hangzhou, China

Antibiotic Number of isolates resistant to antibiotics (%) ESC-resistant S. flexnerivs ESC-resistant S. sonnei (pvalue)
Total (n = 356) S. flexneri( n = 112) S. sonnei(n = 244)  
ESC-resistant (n = 58) Cefotaxime susceptible (n = 54) ESC-resistant vs cefotaxime susceptible (pvalue) ESC-resistant (n = 140) Cefotaxime susceptible (n = 104) ESC-resistant vs cefotaxime susceptible (pvalue)
AMP 348 (97.8) 58 (100) 51(94.4) 0.069 140(100) 99(95.2) 0.009 NA
PIP 298 (83.7) 58(100) 46(85.2) 0.002 140(100) 54 (51.9) <0.001 NA
SAM 136 (38.2) 56(96.6) 46(85.2) 0.035 34(24.3) 0 (0.0) <0.001 <0.001
TZP 1 (0.3) 1 (1.7) 0 (0.0) 3.332 0 (0.0) 0 (0.0) NA 0.119
CAZ 59 (16.6) 34(58.6) 0 (0.0) <0.001 25(17.9) 0 (0.0) <0.001 <0.001
FEP 66 (18.5) 34(58.6) 0 (0.0) <0.001 32(22.9) 0 (0.0) <0.001 <0.001
FOX 8 (2.2) 3 (5.2) 0 (0.0) 0.090 5 (3.6) 0 (0.0) 0.056 0.618
IPM 0(0.0) 0(0) 0 (0.0) NA 0 (0.0) 0 (0.0) NA NA
SXT 304 (85.4) 43(74.1) 25(46.3) 0.003 135(96.4) 101(97.1) 0.766 <0.001
CIP 86 (24.2) 43 (74.1) 39 (72.2) 0.819 3 (2.1) 1 (1.0) 0.485 <0.001
LEV 57 (16.0) 31(53.4) 20(37.0) 0.081 3 (2.1) 3 (2.9) 0.692 <0.001
β-lactam antibiotic + SXT + CIP or LEV 69 (19.4) 36 (62.1) 23 (42.6) 0.039 6 (4.3) 4 (3.8) 0.864 <0.001
  1. AMP, ampicillin; PIP, piperacillin; SAM, ampicillin/sulbactam; TZP, piperacillin/tazobactam; FEP, cefepime; FOX, cefoxitin; IMP, imipenem; SXT, trimethoprim/sulfamethoxazole; CIP, ciprofloxacin; LEV, levofloxacin.
  2. p < 0.05 were considered statistically significant.
  3. NA, not available.
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