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Table 3 Results of interferon-γ release assays and tuberculin skin test in adults and children BCG-unvaccinated

From: Correlation between tuberculin skin test and IGRAs with risk factors for the spread of infection in close contacts with sputum smear positive in pulmonary tuberculosis

  

Adults

Children

Technique

Degree of exposure

Degree of exposure

> 6 h daily

< 6 h daily

Total

p

> 6 h daily

< 6 h daily

Total

p

TST

Positive

18 (94.7)

28 (90.3)

46 (92)

0.820

2 (100)

9 (90)

11 (91)

0.999

Negative

1 (5.3)

3 (9.7)

4 (8)

 

0 (0)

1 (10)

1 (9)

QFN-G-IT

Positive

13 (68.4)

14 (45.2)

27 (54)

0.173

2 (100)

7 (70)

9 (75)

0.999

Negative

6 (31.6)

17 (54.8)

23 (46)

 

0 (0)

3 (30)

3 (25)

Indeterminate

0 (0)

0 (0)

0 (0)

 

0 (0)

0 (0)

0 (0)

T.SPOT-TB

Positive

15 (78.9)

18 (58)

33 (66)

0.223

2 (100)

8 (80)

10 (83.3)

0.999

Negative

4 (21.1)

11 (35.5)

15 (30)

 

0 (0)

2 (20)

2 (16.7)

Indeterminate

0 (0)

2 (6.5)

2 (4)

 

0 (0)

0 (0)

0 (0)

  1. Data are presented as n (%). BCG: Bacille Calmette-Guérin. TST: tuberculin skin test. QFN-G-IT: Quantiferon-TB Gold in tube.
  2. Two-tailed statistical test was used to compare the qualitative results of TST, QFN-G-IT and T-SPOT.TB, respectively, between the two degree of exposure categories in adults and children.