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Table 2 General discriminate analysis of five marker combinations to discriminate active TB and household contacts

From: Combination of gene expression patterns in whole blood discriminate between tuberculosis infection states

  Household contacts TB cases    
  Resubstitution classification Leave-one-out cross Resubstitution classification Leave-one-out cross Wilks lambda   
Genes Matrix Validation Matrix Validation Value f p value
Bcl2, BLR1, FcγR1A, R1A, IFNγ, IL4δ2 95.65 91.3 95.83 95.83 0.74 14 <0.001
Bcl2, FcγR1A, IFNγ, IL4δ2, MARCO 91.3 91.3 95.83 91.66 0.72 15.8 <0.001
Bcl2, BLR1,CD163, FcγR1A, IL4δ2 95.65 95.65 91.66 87.5 0.75 13.65 <0.001
Bcl2, BLR1, FcγR1A, IL4δ2, MARCO 95.65 95.65 95.83 91.66 0.73 14.95 <0.001
Bcl2, CD19, FcγR1A, IL4δ2, MARCO 95.65 95.65 91.66 91.66 0.75 13.21 <0.001
Bcl2, BLR1, CD19, FcγR1A, IL4δ2 91.3 91.3 95.83 87.5 0.77 11.98 0.0013
Bcl2, BPI, FcγR1A, IL4δ2, MARCO 95.65 95.65 91.66 95.83 0.72 16.11 <0.001
BLR 1, FcγR1A, IFNγ, IL4δ2, MMp9 95.65 86.95 95.83 91.66 0.75 13.46 <0.001
BLR 1, FcγR1A, IFNγ, IL4d2, RAB13 91.3 86.95 95.83 91.66 0.76 13.13 <0.001
BLR2, FcγR1A, IL4δ2, MARCO, SPP1 95.65 95.65 95.83 87.5 0.71 16.7 <0.001
  1. Percentage indicates the proportion of groups discriminated using the combination of markers; and f is the measure of fit.