Patients presenting to the hospital with MRSA pneumonia: differentiating characteristics and outcomes with empiric treatment

Table 4 Comparison of patient characteristics and outcomes of those with MRSA pneumonia who received empiric vs directed anti-MRSA therapy

Characteristics	Empiric n = 88 (%)	Directed n = 46 (%)	p value
Age [median (IQR^a)]*	81 (72.3,88)	85.5 (69.8,93)	0.35
Residence prior to admission
Home	15 (17)	20 (43)	0.004
SNF	72 (82)	26 (57)	0.004
APACHE II score [mean, SD^b]^Y	17.9 ± 6.9	13.1 ± 5.2	<0.0001
PSI score [mean, SD]^Y	153.4 ± 36.82	131.3 ± 34.9	0.0011
Mechanical ventilation	33 (38)	14 (30)	0.45
Duration of mechanical ventilation [median IQR]*	3 (2,7)	6 (2.5,20.75)	0.064
Vasopressor use	37 (42)	8 (17)	0.0041
Outcomes
Time to reach clinical stability [median (IQR)]*	7 (4,10)	6 (3.5,11.5)	0.47
Clinical response	55 (63)	35 (76)	0.12
Mortality at 28 days	24 (27)	5 (11)	0.029
Readmission within 30 days	11 (17)	7 (18)	0.79
Length of hospital stay of survivors [median (IQR)]*	10 (6,15)	8.5 (7,14.3)	0.50

NOTE: ^aIQR = interquartile range; ^bSD = standard deviation; SNF = skilled nursing facility; PSI = Pneumonia Severity Index; APACHE = Acute Physiology and Chronic Health Evaluation.
Chi-square test done for categorical variables; p value < 0.05 denotes significance.
*Wilcoxon-Mann-Whitney test, p value < 0.05 denotes significance.
^YStudent’s t-test, p value < 0.05 denotes significance.

ISSN: 1471-2334