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Table 3 Correlations between cytokines expressed in cutaneous and mucosal lesions detected as protein and mRNA a

From: Interleukin 32γ (IL-32γ) is highly expressed in cutaneous and mucosal lesions of American Tegumentary Leishmaniasis patients: association with tumor necrosis factor (TNF) and IL-10

 

CLb

MLc

Correlations

n

r

p

n

r

p

IL-32 x TNF

21

-0.15

0.51

9

0.88

0.003*

IL-32 x IL-10

22

-0.03

0.90

8

0.11

0.79

TNF x IL-10

20

0.38

0.10

8

0.38

0.36

mRNA IL-32 vs. mRNA TNF

8

-0.17

0.70

7

-0.21

0.66

mRNA IL-32 vs. mRNA IL-10

8

-0.17

0.70

7

0.18

0.71

mRNA TNF vs. mRNA IL-10

10

0.28

0.43

6

0.65

0.18

  1. aIL-32, TNF and IL-10 proteins were detected by IHC and IL-32γ, TNF and IL-10 mRNA were detected by qPCR, in biopsy fragments of lesions from bCutaneous leishmaniasis (CL) and cMucosal leishmaniasis (ML) patients. n = number of samples; r = Spearman´s correlation test. *p < 0.05.