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Table 2 Infant CD4, CD19 and CD8 parameters at 2 months of age

From: Impact of maternal HIV-1 viremia on lymphocyte subsets among HIV-exposed uninfected infants: protective mechanism or immunodeficiency

Maternal viral load   CD4 (mean, 95% CI) p Adjusted CD4 (mean, 95% CI) p CD19 (mean, 95% CI) p Adjusted CD19 (mean, 95% CI) p CD8 (mean, 95% CI) p Adjusted CD8 (mean, 95% CI) P
>1000 Relative* 44.3 (41.5–47.0) 0.007 43.5 (40.6–46.3) 0.001 28.7 (26.1–31.4) 0.003 29.3 (26.4–32.2) 0.001 15.5 (14.0–17.1) 0.90 16.0 (14.4–17.6) 0.58
  Absolute** 2432 (2072–2792) 0.02 2395 (2009–2781) 0.022 1479 (1255–1703) 0.79 1510 (1272–1747) 0.49 849 (713–985) 0.26 868 (721–1015) 0.94
50–1000 Relative 48.7 (46.2–51.3) 0.74 48.6 (46.1–51.0) 0.99 23.8 (21.3–26.4) 0.65 24.2 (21.7–26.7) 0.96 15.8 (14.4–17.2) 0.68 15.6 (14.2–17.0) 0.73
  Absolute 2872 (2533–3210) 0.94 2888 (2548–3229) 0.96 1375 (1165–1585) 0.53 1416 (1206–1625) 0.57 952 (824–1079) 0.77 947 (817–1077) 0.80
<50 Relative 48.3 (47.3–49.2) Ref 48.5 (47.6–49.5) Ref 24.5 (23.5–25.4) Ref 24.1 (23.2–25.1) Ref 15.4 (14.9–16.0) Ref 15.5 (15.0–16.1) Ref
  Absolute 2884 (2759–3010)   2878 (2751–3005)   1446 (1369–1523)   1419 (1342–1497)   931 (884–979)   930 (882–979)  
  1. *Relative counts are reported as percentages.
  2. **Absolute counts are reported as cells/mm3.
  3. Comparing means in group VL > 1000 and VL 50–1000 to VL < 50 (reference group) using sum of least squares.
  4. Adjusted for maternal CD4, maternal ART use, infant ART use, gender, gestational age and race in a multivariable analysis of variance.