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Table 4 Total cohort: multivariate analysis of factors associated with embolism*

From: Predicting the occurrence of embolic events: an analysis of 1456 episodes of infective endocarditis from the Italian Study on Endocarditis (SEI)

  Odds ratio 95% CI p ≤ †
Age 1.0 1.0 – 1.0 NS
HIV infection 0.8 0.3 – 2.0 NS
Cancer 1.10 0.7 – 1.9 NS
Chronic liver disease 1.4 0.9 – 2.2 NS
Mitral vs aortic valve 1.0 0.7 – 1.3 NS
Prosthetic vs native valve 1.8 1.2 – 2.9 0.011
Righ-sided IE 3.9 2.0 – 7.7 <0.0001
Size of vegetation ≥ 13 mm 1.9 1.32.6 <0.0001
Staphylococcus aureus 2.2 1.53.4 <0.0001
Coagulase-negative staphylococci 1.6 1.0 – 2.6 NS
Enterococcus spp. 0.8 0.4 – 1.4 NS
Anticoagulant therapy 0.8 0.5 – 1.3 NS
  1. *N = 1456 IE episodes. Abbreviation: HIV human immunodeficiency virus.
  2. †NS, not significant (p > 0.05).
  3. Bold numbers represent statistically significant differences.