|
Number of IE episodes
|
1456 (100)
|
967 (66.4)
|
339 (23.3)
|
89 (6.1)
|
61 (4.2)
|
|
Age (y)
|
65 (50 to 64)
|
64 (48 to 74)
|
70 (61 to 76)
|
48 (35 to 67)
|
67 (55 to 77)
|
|
Male
|
1018 (70)
|
688 (71)
|
221 (65)
|
61 (69)
|
48 (79)
|
|
Comorbidity and predisposing conditions
| |
|
Native valve disease
|
372 (26)
|
299 (31)
|
60 (18)
|
7 (8)
|
6 (10)
|
|
Diabetes mellitus
|
268 (18)
|
164 (17)
|
79 (23)
|
10 (11)
|
15 (25)
|
|
Chronic liver disease
|
262 (18)
|
169 (18)
|
49 (15)
|
38 (43)
|
6 (10)
|
|
Cancer
|
175 (12)
|
131 (14)
|
28 (8)
|
10 (11)
|
6 (10)
|
|
Chronic intravenous access
|
154 (11)
|
102 (11)
|
34 (10)
|
11 (12)
|
7 (12)
|
|
Current intravenous drug abuse
|
131 (9)
|
81 (8)
|
14 (4)
|
34 (38)
|
2 (3)
|
|
Previous IE
|
118 (8)
|
48 (5)
|
59 (17)
|
7 (8)
|
4 (7)
|
|
Congenital heart disease
|
112 (8)
|
85 (9)
|
16 (5)
|
6 (7)
|
5 (8)
|
|
Immunosuppressive therapy
|
86 (6)
|
70 (7)
|
11 (3)
|
2 (2)
|
3 (5)
|
|
HIV infection
|
52 (4)
|
36 (4)
|
4 (1)
|
10 (11)
|
2 (3)
|
|
Hemodialysis
|
29 (2)
|
21 (2)
|
4 (1)
|
2 (2)
|
2 (3)
|
|
Microbiology
| |
|
Staphylococcus aureus
|
283 (19)
|
181 (19)
|
53 (16)
|
35 (39)
|
14 (23)
|
|
Viridans group streptococci
|
217 (15)
|
172 (18)
|
29 (9)
|
8 (9)
|
8 (13)
|
|
Enterococcus species
|
182 (13)
|
117 (12)
|
53 (16)
|
8 (9)
|
4 (7)
|
|
Coagulase-negative staphylococci
|
147 (10)
|
74 (8)
|
55 (16)
|
4 (5)
|
14 (23)
|
|
Streptococcus bovis
|
142 (10)
|
105 (11)
|
29 (9)
|
7 (8)
|
1 (2)
|
|
Other streptococci
|
59 (4)
|
46 (5)
|
7 (2)
|
3 (3)
|
3 (5)
|
|
Other microorganisms
|
61 (4)
|
36 (4)
|
20 (6)
|
2 (2)
|
3 (5)
|
|
Polymicrobial
|
51 (4)
|
34 (4)
|
10 (3)
|
4 (5)
|
3 (5)
|
|
Fungi
|
20 (1)
|
12 (1)
|
8 (2)
|
0 (0)
|
0 (0)
|
|
HACEK
|
3 (0.2)
|
0 (0)
|
2 (0.6)
|
1 (1)
|
0 (0)
|
|
Microbiology negative
|
291 (20)
|
190 (20)
|
73 (22)
|
17 (19)
|
11 (18)
|
