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Table 3 Non-Hodgkin lymphoma and Kaposi sarcoma in AIDS-associated autopsies

From: The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan

   Total ART (−) patients ART (+) patients Pvalues
   n % n % n %   
All NHL cases   71 100.0% 41 100.0% 25 100.0%   
 Histology DLBCL 53 74.6% 30 73.2% 18 72.0% 0.917  
  BL 4 5.6% 3 7.3% 1 4.0% 0.987 Y
  PEL 5 7.0% 4 9.8% 1 4.0% 0.706 Y
  PBL 1 1.4% 1 2.4% 0 0.0% 0.801 Y
  Other 6 8.5% 2 4.9% 4 16.0% 0.279 Y
  Unknown 2 2.8% 1 2.4% 1 4.0% 0.703 Y
 Site Nodular 1 1.4% 0 0.0% 1 4.0% 0.801 Y
  Extranodular 45 63.4% 28 68.3% 12 48.0% 0.102  
  Both 21 29.6% 11 26.8% 10 40.0% 0.265  
  Unknown 4 5.6% 2 4.9% 2 8.0% 0.987 Y
 PCNS Yes 27 38.0% 18 43.9% 6 24.0% 0.103  
 EBV Positive 52 73.2% 35 85.4% 12 48.0% 0.001  
 KSHV Positive 6 8.5% 5 12.2% 1 4.0% 0.495 Y
 Cause of death Yes 50 70.4% 33 80.5% 16 64.0% 0.137  
All KS cases   38   22   10    
 Site Skin 32 84.2% 19 86.4% 9 90.0% 0.410  
  GI tract 27 71.1% 15 68.2% 8 80.0% 0.705  
  Lung 21 55.3% 11 50.0% 6 60.0% 0.799  
  Lymph node 20 52.6% 13 59.1% 6 60.0% 0.502  
  Other 16 42.1% 0 0.0% 0 0.0% 0.787 Y
 Cause of death Yes 11 29.0% 7 31.8% 2 20.0% 0.791 Y
  1. NHL, Non-Hodgkin lymphoma; DLBCL, diffuse large B-cell lymphoma; BL, Burkitt lymphoma; PEL, primary effusion lymphoma; PBL, plasmablastic lymphoma; PCNS, primary central nervous system lymphoma; EBV, Epstein–Barr virus; KSHV, Kaposi sarcoma-associated herpes virus; KS, Kaposi sarcoma; GI, gastrointestinal. P values were calculated by Chi-square test. Y indicates the use of Chi-square test with Yates correction. Bold font indicates statistical significance.