The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan

Table 3 Non-Hodgkin lymphoma and Kaposi sarcoma in AIDS-associated autopsies

		Total		ART (−) patients		ART (+) patients		Pvalues
		n	%	n	%	n	%
All NHL cases		71	100.0%	41	100.0%	25	100.0%
Histology	DLBCL	53	74.6%	30	73.2%	18	72.0%	0.917
	BL	4	5.6%	3	7.3%	1	4.0%	0.987	Y
	PEL	5	7.0%	4	9.8%	1	4.0%	0.706	Y
	PBL	1	1.4%	1	2.4%	0	0.0%	0.801	Y
	Other	6	8.5%	2	4.9%	4	16.0%	0.279	Y
	Unknown	2	2.8%	1	2.4%	1	4.0%	0.703	Y
Site	Nodular	1	1.4%	0	0.0%	1	4.0%	0.801	Y
	Extranodular	45	63.4%	28	68.3%	12	48.0%	0.102
	Both	21	29.6%	11	26.8%	10	40.0%	0.265
	Unknown	4	5.6%	2	4.9%	2	8.0%	0.987	Y
PCNS	Yes	27	38.0%	18	43.9%	6	24.0%	0.103
EBV	Positive	52	73.2%	35	85.4%	12	48.0%	0.001
KSHV	Positive	6	8.5%	5	12.2%	1	4.0%	0.495	Y
Cause of death	Yes	50	70.4%	33	80.5%	16	64.0%	0.137
All KS cases		38		22		10
Site	Skin	32	84.2%	19	86.4%	9	90.0%	0.410
	GI tract	27	71.1%	15	68.2%	8	80.0%	0.705
	Lung	21	55.3%	11	50.0%	6	60.0%	0.799
	Lymph node	20	52.6%	13	59.1%	6	60.0%	0.502
	Other	16	42.1%	0	0.0%	0	0.0%	0.787	Y
Cause of death	Yes	11	29.0%	7	31.8%	2	20.0%	0.791	Y

NHL, Non-Hodgkin lymphoma; DLBCL, diffuse large B-cell lymphoma; BL, Burkitt lymphoma; PEL, primary effusion lymphoma; PBL, plasmablastic lymphoma; PCNS, primary central nervous system lymphoma; EBV, Epstein–Barr virus; KSHV, Kaposi sarcoma-associated herpes virus; KS, Kaposi sarcoma; GI, gastrointestinal. P values were calculated by Chi-square test. Y indicates the use of Chi-square test with Yates correction. Bold font indicates statistical significance.

ISSN: 1471-2334