The prevalence of opportunistic infections and malignancies in autopsied patients with human immunodeficiency virus infection in Japan

Table 1 Characteristics of the patients infected with HIV

Factors	Groupings	Total patients		ART (−) patients		ART (+) patients		Pvalue
		n	%	n	%	n	%
Total		225*	100%	136	100%	66	100%
Sex	Male	214	95.1%	128	94.1%	63	95.5%	0.695**
	Female	11	4.9%	8	5.9%	3	4.5%
Age at death	<10 years	0	0.0%	0	0.0%	0	0.0%	0.028***
	11–20	2	0.9%	2	1.5%	0	0.0%
	21–30	30	13.3%	22	16.2%	6	9.1%
	31–40	60	26.7%	34	25.0%	19	28.8%
	41–50	69	30.7%	48	35.3%	14	21.2%
	51–60	34	15.1%	18	13.2%	14	21.2%
	61–70	24	10.7%	10	7.4%	10	15.2%
	71–80	5	2.2%	1	0.7%	3	4.5%
	>81	0	0.0%	0	0.0%	0	0.0%
	Unknown	1	0.4%	1	0.7%	0	0.0%
Risk factor	Homosexual	80	35.6%	52	38.2%	24	36.4%	0.800**
	Heterosexual	38	16.9%	24	17.6%	10	15.2%
	Blood product	37	16.4%	29	21.3%	7	10.6%
	Other	9	4.0%	5	3.7%	4	6.1%
	Unknown	61	27.1%	26	19.1%	21	31.8%
CD4 count before death	<50 cells/μL	122	54.2%	80	58.8%	33	50.0%	0.639***
	51–100	25	11.1%	11	8.1%	14	21.2%
	101–200	13	5.8%	4	2.9%	9	13.6%
	201–300	5	2.2%	5	3.7%	0	0.0%
	301–400	3	1.3%	1	0.7%	2	3.0%
	>401	4	1.8%	1	0.7%	3	4.5%
	Unknown	53	23.6%	34	25.0%	5	7.6%

ART, antiretroviral therapy. ART (+) patients were defined as patients who received any ART during their lifetime, whereas ART (−) patients were as patients who did not receive any ART in their lifetime.
*Total number of patients = 225 and included 23 patients with unknown ART status.
**P values were calculated for the rates of male or homosexuals between ART (−) and (+) patients by Chi-square test.
***P values were calculated for age or CD4 counts between all ART (−) and (+) patients by Mann–Whitney U-test. Bold font indicates statistical significance.

ISSN: 1471-2334