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Table 2 Demographic characteristics of patients treated with rifampin or non-rifampin regimen

From: Factors predictive of treatment failure in staphylococcal prosthetic vascular graft infections: a prospective observational cohort study: impact of rifampin

Population, n = 84 NoRifampicin Rifampicin p
  n = 39, (%) n = 45, (%)  
Age, mean ± SD 68.59 ± 11.23 62.02 ± 10.93 0.006
Diabetes mellitus 10 (40.0%) 15 (60.0%) 0.441
Body mass index, mean ± SD 25.31 ± 4.28 25.72 ± 4.61 0.676
Creatinine clearance <60 ml/min 70.33 ± 31.95 86.07 ± 34.68 0.035
Immunodepression 5 (33.3%) 10 (66.7%) 0.261
Chronic obstructive pulmonary disease 11 (50.0%) 11 (50.0%) 0.15
Coronary disease 24 (50.0%) 24 (50.0%) 0.448
Aortic aneurysm 16 (50.0%) 16 (50.0%) 0.606
Presumed PVGI 1 (12.5%) 7 (87.5%) 0.043
Definite PVGI 38 (50.0%) 38 (50.0%) 0.043
Early definite PVGI (<4 months) 24 (57.1%) 18 (42.9%) 0.049
Late definite PVGI (> 4 months) 14 (41.2%) 20 (58.8%) 0.426
Extracavitary PVGI 19 (50.0%) 19 (50.0%) 0.550
Fever > 38°C 26 (46.4%) 30 (53.6%) 0.865
Fissuration/disruption 2 (22.2%) 7 (77.8%) 0.125
False aneurysm 7 (63.6) 4 (36.4) 0.209
White blood cells count (G/l) 11410.7 ± 4463.2 10882.1 ± 4162.3 0.0645
Mean ± SD
Autologous vein 9 (75.0%) 3 (25.0%) 0.032
Arterial homo/allograft 9 (37.5%) 15 (62.5%) 0.299
New prosthesis 4 (50.0%) 4 (50.0%) 0.831
Debridement 2 (50.0%) 2 (50.0%) 0.883
Medical treatment (no surgery) 5 (38.5%) 8 (61.5%) 0.531
Adequate empirical antibiotherapy 37 (46.8%) 42 (53.2%) 0.766
New surgery 9 (36.0%) 16 (64.0%) 0.165
Admission to intensive care unit 22 (62.9%) 13 (37.1%) 0.010
Septic shock at initial presentation 8 (53.3%) 7 (46.7%) 0.554
Post-operative dialysis 3 (75.0%) 1 (25.0%) 0.240
Death related to PVGI 11 (78.6%) 3 (21.4%) 0.008