Table 1 Demographic characteristics of 84 patients with staphylococcal PVGI
Population, n = 84 | Remission | Failure | p |
|---|---|---|---|
n = 63, (%) | n = 21, (%) | ||
Age, mean ± SD | 64.1 ± 11 | 67.8 ± 12 | 0.2 |
Diabetes mellitus | 19 (30.1) | 6 (28.5) | 0.89 |
Body mass index, mean ± SD | 25 ± 4.7 | 26 ± 4.3 | 0.46 |
Creatinine clearance < 60 ml/min | 15 (23.8) | 9 (42.8) | 0.09 |
Immunodepression | 11 (17.4) | 4 (19.1) | 0.86 |
Chronic obstructive pulmonary disease | 14 (22.2) | 8 (38.1) | 0.15 |
Coronary disease | 35 (55.5) | 13 (61.9) | 0.61 |
Aortic aneurysm | 20 (31.7) | 12 (57.1) | 0.03 |
Presumed PVGI | 7 (11.1) | 1 (4.7) | 0.39 |
Definite PVGI | 56 (88.9) | 20 (95.2) | 0.39 |
Early definite PVGI (<4 months) | 30 (47.6) | 12 (57.1) | 0.45 |
Late definite PVGI (> 4 months) | 26 (41.2) | 8 (38.1) | 0.79 |
Extracavitary PVGI | 31 (49.9) | 6 (29.6) | 0.07 |
Fever > 38°C | 37 (58.7) | 19 (90.5) | 0.009 |
Fissuration/disruption | 7 (11.1) | 2 (9.5) | 0.02 |
False aneurysm | 9 (14.2) | 2 (9.5) | 0.6 |
White blood cells count (G/l) | 11.196 ± 4.6 | 11.022 ± 3.48 | 0.88 |
Mean ± SD | |||
Autologous vein | 10 (15.8) | 2 (9.5) | 0.47 |
Arterial homo/allograft | 20 (31.7) | 4 (19) | 0.26 |
New prosthesis | 6 (9.5) | 2 (9.5) | 1 |
Debridement | 16 (25.4) | 8 (38.1) | 0.26 |
Medical treatment (no surgery) | 9 (9.5) | 4 (19) | 0.6 |
Adequate empirical antibiotherapy | 60 (95.2) | 19 (90.4) | 0.42 |
New surgery | 15 (23.8) | 10 (47.6) | 0.02 |
Rifampin combination | 38 (60.3) | 7 (33.3) | 0.03 |
Admission to intensive care unit | 21 (33.3) | 14 (66.6) | 0.007 |
Septic shock at initial presentation | 7 (11.1) | 8 (38.1) | 0.005 |
Post-operative dialysis | 0 (0) | 4 (19) | 0.001 |
Death related to PVGI | 0 (0) | 14 (66.6) | 0.001 |
Death not related to PVGI | 6 (9.5) | 2 (9.5) | 1 |
Median follow-up (interquartile) (days) | 605 ± 406 | 621 ± 455 | 0.2 |