From: Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis
Species | AMB (µg/mL) | FLC (µg/mL) | ITC (µg/mL) | VRC (µg/mL) | PCZ (µg/mL) | 5FC (µg/mL) | CAS (µg/mL) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | MIC | MFC | ||
S. brasiliensis (n = 22) | Range | 1-8 | 2 - >16 | >64 | >64 | 0.25 - 4 | 1 - > 16 | 2 - >16 | 16 - >16 | 0.5 - 2 | 1 - >16 | 64 - >64 | >64 | >16 | >16 |
50% | 4 | 4 | >64 | >64 | 1 | 16 | 16 | >16 | 1 | >16 | >64 | >64 | >16 | >16 | |
90% | 4 | 16 | >64 | >64 | 2 | >16 | >16 | >16 | 2 | >16 | >64 | >64 | >16 | >16 | |
S. schenckii (n = 39) | Range | 1 - >16 | 2 - >16 | >64 | >64 | 0.25 - >16 | 0.5 - > 16 | 4 - >16 | 4 - >16 | 0.06 - >16 | 1 - >16 | 64 - >64 | 64 - >64 | 2 - >16 | >16 |
50% | 8 | 16 | >64 | >64 | 1 | 16 | 16 | >16 | 1 | >16 | 64 | >64 | >16 | >16 | |
90% | >16 | >16 | >64 | >64 | 4 | >16 | >16 | >16 | 2 | >16 | >64 | >64 | >16 | >16 | |
S. globosa (n = 4) | Range | 2 - >16 | 4 - >16 | >64 | >64 | 0.5 - >16 | 0.5 - >16 | 2 - 8 | 8 - >16 | 0.5 - 16 | 1 - >16 | 8 - >64 | >64 | 8 - > 16 | >16 |
50% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
90% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
S. mexicana (n = 3) | Range | 8 - >16 | 8 - >16 | >64 | >64 | 2 - >16 | 2 - >16 | 1 - >16 | 16 - > 16 | 1 - >16 | >16 | 64 - >64 | >64 | 8 - >16 | >16 |
50% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
90% | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |
Overall (n = 68) | Range | 1 - >16 | 2 - >16 | >64 | >64 | 0.25 - >16 | 0.5 - >16 | 1 - >16 | 4 - >16 | 0.06 - >16 | 1 - >16 | 8 - >64 | 64 - >64 | 2 - >16 | >16 |
50% | 4 | 16 | >64 | >64 | 1 | >16 | 16 | >16 | 1 | >16 | >64 | >64 | >16 | >16 | |
90% | >16 | >16 | >64 | >64 | >16 | >16 | >16 | >16 | 2 | >16 | >64 | >64 | >16 | >16 |