Figure 7

Abridgement of the parasitic polymorphism of Coccidioides spp. (a) microcolony with hifas/esferulas-1 coexisting with granuloma-2; (b, c, d) morphological differentiation: spores-3, spores producing hypha-4, spherules at different stages of maturation-5, with endospores-6, empty-7, releasing endospores-8 or producing hyphae-9; branching hyphae with barrel-sharped or racket-sharped-10, and ovoid/spherical-11 artroconidia. Lung tissue. (a) 10X, Periodic acid-Schiff (PAS); (b) 40X Grocott methenamine silver (GMS) staining protocol; (c) 40X, PAS (d) 100X GMS.