Skip to main content

Table 2 Mycolactone detection by mass spectrometry and cytotoxicity assay in patients with M. ulcerans disease sampled for M. ulcerans culture

From: Kinetics of mycolactone in human subcutaneous tissue during antibiotic therapy for Mycobacterium ulcerans disease

Time

Week 0

Week 6

Week 12

Mycolactone detection

Culture result

Culture result

Culture result

Positive

Negative

Positive

Negative

Positive

Negative

Cytotoxicity positive

35

17

7

7

2

0

Cytotoxicity negative

5

3

0

1

0

1

Total (1)

40

20

7

8

2

1

MS positive

26

16

6

7

0

0

MS negative

14

4

0

1

2

1

Total (2)

40

20

6

8

2

1

  1. MS - Mass spectrometry. Total (1) represents sub-total of comparison of mycolactone detection by cytotoxicity and culture results. Total (2) represents sub-total of comparison of mycolactone detection by mass spectrometry and culture results.