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Table 2 Monthly drug use density (expressed as RDD per 100 patient days) trends in the medical service pre- (baseline) and post-intervention as estimated in a single-level interrupted time-series model (P values in parentheses)

From: Feasibility and impact of an intensified antibiotic stewardship programme targeting cephalosporin and fluoroquinolone use in a tertiary care university medical center

 

Cephalosporins

Fluoroquinolones

Penicillins

TOTAL

Baseline

−0.02

−0.10

−0.03

−0.13

trend β1

(ns)

(<0.001)

(ns)

(0.038)

Post-intervention

−0.52 (<0.001)

−0.40 (<0.001)

+0.34 (<0.001)

−1.10 (<0.001)

trend change β2

    

Intercept β0

16.61 (<0.001)

19.96 (<0.001)

16.11 (<0.001)

88.73 (<0.001)

N

63

63

63

63