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Table 2 Patients showing high or low risk for a probiotic-induced sepsis

From: Do children’s upper respiratory tract infections benefit from probiotics?

Type of risk

Patients

High

Immunocompromised patients

 

Premature neonates

Low

Patients with a central venous catheter

 

Patients receiving probiotics by jejunostomy

 

Patients concomitantly receiving broad spectrum antibiotics to which the probiotic is resistant

 

Patients receiving probiotics with high mucosal adhesion properties or showing an established pathogenicity

 

Patients with cardiac valvular disease (for Lactobacillus probiotics only)

  1. The presence in the same patients of a single major or more than one minor risk factor dictates caution when using probiotics.