Skip to main content

Table 1 Samples utilised for the assays

From: Factors affecting immunogenicity of BCG in infants, a study in Malawi, The Gambia and the UK

 

Malawi

The gambia

Purpose of collection

Culture supernatant

30

24

42plex bead assay

Season of birth

Rainy season

16

0

Dry season

14

24

Plasma

63 (57)

 

Zn2+ & CRP assay

Season of birth

Rainy season

40 (38)

 

Dry season

23 (19)

 

BCG given time (week after birth)

1

1

 

Mean Age at test (month)

3.2 (2.8-6.5)

3.1 (1.8-3.8)

 

Mean body weight at test (kg)

6.3 (4.4-9.2)

6.2 (4.2-7.7)

 
  1. Culture supernatants obtained from Malawian (n = 30) and Gambian infants (n = 24) tested at 3 months post BCG vaccination were utilised to measure 42 cytokine/chemokine signatures. In Malawi, the rainy season is from January to May and the dry season is from June to December. In The Gambia, the wet season is from July to December and the dry season is from January to June. For testing CRP and zinc (Zn2+) levels in plasma, 63 plasma samples were tested from Malawian infants 3 months post BCG vaccination. Among the plasma samples selected, 6 samples were excluded from CRP testing as these infants were immunized with DPT, Hib and IPV within 7 days prior to blood collection. The number of samples excluding those who had DPT, Hib and IPV immunization within 7 days before the blood collection is indicated in parentheses.